Sensitive skin and skin irritation. Characteristics and diagnostic tools.

Completed

Conditions: Sensitive skin
skin irritation
10014982

Registration Number: NL-OMON38547

Lead Sponsor: Philips Research

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Completed

Sex: Not specified

Target Recruitment: 48

Inclusion Criteria

Specification: research protocol (section 3)
To enter this pilot study, volunteers must meet the following criteria:
- Age between 18 and 65 years of age
- Volunteers must be willing to give a written informed consent
- Volunteers must have skin type II or III (Fitzpatrick scale)
- Non-sensitive skin or sensitive skin (both determined by a questionnaire)

Exclusion Criteria

•Any skin disease at the moment of screening.
•Volunteers with a predisposition to respond allergic. History of atopic dermatitis, asthma, allergic rhinitis or allergic conjunctivitis.
•Volunteers with a allergic contact dermatitis in history.
•Volunteers with skin type I, IV, V or VI (Fitzpatrick scale)
•Use of immunosuppressive drugs (NSAIDs; biologicals; topical or systemic corticosteroids)
• Recent excessive sun exposure or tanning (<2 weeks).
volunteers with predisposition to develop hypertrophic scars.
Volunteers with bleeding disorders.

Study & Design

Study Type: Observational invasive

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Main study parameters/endpoints: This pilot study is an explorative<br /><br>observational study with the objective to detect difference between sensitive<br /><br>skin and non-sensitive skin. Baseline parameters and skin response following<br /><br>different stimuli are investigated. The main parameters are abnormal<br /><br>differentiation parameters and biophysical parameters as a* value, stratum<br /><br>corneum hydration and transepidermal water loss. </p><br>

Secondary Outcome Measures