The Effectiveness of Dexmedetomidine versus Tramadol as pretreatment in Alleviating Propofol injection pain A Comparative Study
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- To assess the effectiveness of dexmedetomidine and tramadol as pre-treatment in alleviating propofol injection pain.
研究概览
简要总结
Patients fulfilling the inclusion crietria was divided into 2 groups a pneumatic torniquet of 70mmhg was tied on same hand where IV was secured ,GROUP D - dexmeditomedine 0.25mcg/kg and GROUP T - Tramadol 50mg was given as pretreatment over 10 seconds after 60seconds 25percent of the calculated dose of propofol was given 15 seconds later pain severity score was assessed using McCrick and Hunter scale.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Participant Blinded
入排标准
- 年龄范围
- 20.00 Year(s) 至 50.00 Year(s)（—）
- 性别
- All
入选标准
- •1 Informed consent 2 Age between 20 to 50 years.
- •3 ASA I and II patients .
- •4 Posted for elective surgery under general Anaesthesia.
排除标准
- •1 Pregnant and lactating women.
- •2 Patients with hypersensitivity or allergies to Dexmedetomidine, Propofol or Tramadol.
- •3 Diabetes, cardiovascular diseases, liver and kidney disorders, psychiatric disorders.
结局指标
主要结局
To assess the effectiveness of dexmedetomidine and tramadol as pre-treatment in alleviating propofol injection pain.
时间窗: Pain assessment will be done 15 seconds after injection of 25% of calculated dose.Pain severity was assessed using a McCririck and Hunter Scale - a 4-point verbal rating scale. | 0 - No pain | 1 - Mild pain (pain reported only in response to questioning without any behavioural signs) | 2 - Moderate pain (pain reported in response to questioning and accompanied by a behavioural sign or pain reported spontaneously without questioning). | 3 - Severe pain (strong vocal response or response accompanied by facial grimacing, arm withdrawal or tears).
次要结局
未报告次要终点
研究者
Dr Mangala C Patil
Sapthagiri Institute of Medical Sciences and Research Centre