Effects of roflumilast on cognition in healthy adults: a behaviour-EEG study - Roflumilast and cognition

niversiteit Maastricht0 个研究点目标入组 44 人开始时间: 待定最近更新: 2024年5月6日

适应症

试验速览

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•Male or female, 18 to 35 years of age, healthy (i.e. absence of all exclusion criteria), normal static binocular acuity (corrected or uncorrected), body mass index between 18.5 and 30, willingness to sign an informed consent, positive evaluation on the medical and memory screening

•Volunteers who suffer from, or have a history of cardiac, hepatic, renal, pulmonary, neurological, gastrointestinal, haematological, or psychiatric illness, will be excluded. Other exclusion criteria are excessive drinking (>20 glasses of alcohol containing beverages a week), pregnancy or lactation, use of chronic medication other than oral contraceptives, use of recreational drugs from 2 weeks before until the end of the experiment, smoking, ortostatic hypotension, lactose intolerance, and any sensory or motor deficits which could reasonably be expected to affect test performance. Those volunteers who have a first-degree relative with a psychiatric disorder or a history of depressive disorder with or without suicidal risk will be excluded as well.

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