Effects of Phenolic Acids on Endothelial Function
Not Applicable
Completed
- Conditions
- Healthy
- Interventions
- Other: Phenolic acids
- Registration Number
- NCT01772784
- Lead Sponsor
- Société des Produits Nestlé (SPN)
- Brief Summary
Epidemiological studies suggest dietary (poly) phenols decrease the risk of death from cardiovascular diseases. (Poly)phenol-rich foods include fruits and vegetables as well as tea, coffee, red wine, and chocolate. The aim of the present study is to investigate whether endothelial function is altered by ingestion of phenolic acids. Moreover, the investigators will evaluate the effect of phenolic acids on blood pressure and platelet adhesion.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- Male
- Target Recruitment
- 24
Inclusion Criteria
- Healthy
- males
- Smokers
Exclusion Criteria
Any food allergy
- Abnormal blood pressure defined as follow: systolic <100 or >160 mmHg and diastolic <50 or >100mmHg
- Regular consumption of medication within 2 months before the study inclusion
- Caffeine intake 1 day before screening measurements (and 1 day before each visit),
- Any intake of multivitamin-tablets and other supplemental compounds 10 days before the study start and throughout the study.
- Excessive alcohol intake defined as > 280 g per week
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- CROSSOVER
- Arm && Interventions
Group Intervention Description phenolic acids Phenolic acids Maltodextrine + Phenolic acids placebo Phenolic acids Maltodextrine phenolic acid Phenolic acids Maltodextrine + Phenolic acids polyphenol Phenolic acids -
- Primary Outcome Measures
Name Time Method endothelial dysfunction 1 hour
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Swiss Cardiovascular Center Bern, University Hospital
🇨🇭Bern, Switzerland