NCT01772784已完成不适用
Effects of Phenolic Acids on Endothelial Function
Société des Produits Nestlé (SPN)2 个研究点 分布在 1 个国家目标入组 24 人开始时间: 2012年6月1日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 24
- 试验地点
- 2
- 主要终点
- endothelial dysfunction
研究概览
简要总结
Epidemiological studies suggest dietary (poly) phenols decrease the risk of death from cardiovascular diseases. (Poly)phenol-rich foods include fruits and vegetables as well as tea, coffee, red wine, and chocolate. The aim of the present study is to investigate whether endothelial function is altered by ingestion of phenolic acids. Moreover, the investigators will evaluate the effect of phenolic acids on blood pressure and platelet adhesion.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 盲法
- Double (Participant, Investigator)
入排标准
- 年龄范围
- 18 Years 至 75 Years（Adult, Older Adult）
- 性别
- Male
- 接受健康志愿者
- 是
入选标准
- 未提供
排除标准
- •Any food allergy
- •Abnormal blood pressure defined as follow: systolic <100 or >160 mmHg and diastolic <50 or >100mmHg
- •Regular consumption of medication within 2 months before the study inclusion
- •Caffeine intake 1 day before screening measurements (and 1 day before each visit),
- •Any intake of multivitamin-tablets and other supplemental compounds 10 days before the study start and throughout the study.
- •Excessive alcohol intake defined as > 280 g per week
结局指标
主要结局
endothelial dysfunction
时间窗: 1 hour
次要结局
未报告次要终点
研究者
研究点 (2)
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