跳至主要内容
临床试验/NCT00563940
NCT00563940已完成不适用

Short-term Effects of Intravitreal Bevacizumab and Triamcinolone in Patients With Diabetic Macular Edema

Insel Gruppe AG, University Hospital Bern1 个研究点 分布在 1 个国家目标入组 30 人开始时间: 2007年3月最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
30
试验地点
1
主要终点
Central retinal thickness

研究概览

简要总结

Diabetic macular edema is a common complication of ocular diabetes mellitus and can cause blindness. Hypoxygenation of the retina stimulates tissue mediators, especially different subtypes of vascular endothelial growth factor (VEGF). VEGF is responsible for proliferation, extension and increased permeability of the vessels. The aim of our study was to examine the short-term effect of intravitreal bevacizumab (Avastin® 1.25 mg in 0.05 ml) and triamcinolone on visual acuity and central retinal thickness in patients with clinically significant diabetic macular edema (CSME).

研究设计

研究类型
Observational
观察模型
Case Only
时间视角
Prospective

入排标准

年龄范围
20 Years 至 80 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • clinical significant macular edema

排除标准

  • retinal thickness < 250 µm

结局指标

主要结局

Central retinal thickness

时间窗: 4, 8, 12, 24, 72, and 168 hours

次要结局

  • BCVA(4, 8, 12, 24, 72, and 168 hours)

研究者

申办方类型
Other
责任方
Sponsor

研究点 (1)

Loading locations...

相似试验

Short-term Effects of Intravitreal Bevacizumab and... | 临床试验