Iron Metabolism in Dragon Boat Athletes

Not Applicable

Completed

• Conditions: Anaemia
• Interventions: Other: specific dragon boating training intervention; Other: specific dragon boat intervention

• Registration Number: NCT01431118
• Lead Sponsor: University of Giessen

Brief Summary

The purpose of the study is:

* To investigate the effect of sport-specific stress in the iron metabolism of dragon boat athletes

* To investigate the effects of sport-specific stress in the activity of pro-hepcidin and hepcidin

Detailed Description

This investigation evaluates the effects of sport-specific stress in iron metabolism of dragon boat athletes. Recent studies showed a significant increase in hepcidin activity under exercise (Röcker L. et al.(2005): Iron regulatory protein hepcidin is increased in female athletes after a marathon. European Journal of Applied Physiology, S. 95, 569-571)which possibly influences the iron metabolism.

In particular in this investigation the activity of pro-hepcidin and hepcidin under sport-specific stress is analysed. Therefore elite dragonboat athletes will be included to this study. Every athlete is tested once. At one exercise day from every athlete the iron metabolism especially the change of hepcidin, prohepcidin and iron before and after a specific dragonboat intervention is analysed.

Study Timeline

• Study Start: 2011-04
• Study First Submitted: 2011-08-31
• Study First Submitted QC: 2011-09-07
• Study First Posted: 2011-09-09
• Primary Completion: 2012-04
• Study Completion: 2012-04
• Status Verified: 2012-07
• Last Update Submitted: 2012-07-21
• Last Update Posted: 2012-07-24

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

• athletes performing dragon boat sport

Exclusion Criteria

• acute clinically significant intercurrent diseases

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
sports intervention male	specific dragon boating training intervention	male athletes of the german national dragon boat team
sports intervention women	specific dragon boat intervention	women athletes of the german national dragon boat team

Primary Outcome Measures

Name	Time	Method
change from Baseline in prohepcidin after performing dragonboating	pre and post exercise intervention at the same day	one meassurement of prohepcidin immediate before and within three hours after performing two to four specific dragonboat interventions at the same day

Secondary Outcome Measures

Name	Time	Method
haematocrit	pre and post exercise intervention at the same day	one meassurement of haematocrit immediate before and within three hours after performing two to four specific dragonboat intervention at the same day
value of reticulocytes	pre exercise	one meassurement of reticulocytes immediate before performing two to four specific dragonboat interventions
value of hypochromic erythrocytes	pre exercise	one meassurement of hypochromic erythrocytes immediate before performing two to four specific dragonboat interventions
change from Baseline in serum iron after performing dragonboating	pre and post exercise intervention at the same day	one meassurement of serum iron immediate before and within three hours after performing two to four specific dragonboat interventions at the same day
value of transferrin	pre exercise	one meassurement of transferrin immediate before performing two to four specific dragonboat interventions
value of transferrin saturation	pre exercise	one meassurement of transferrin saturation immediate before performing two to four specific dragonboat interventions
value of ferritin	pre exercise	one meassurement of ferritin immediate before performing two to four specific dragonboat interventions
change from Baseline in hepcidin after performing dragonboating	pre and post exercise intervention at the same day	one meassurement of hepcidin immediate before and within three hours after performing two to four specific dragonboat interventions at the same day