Iron Metabolism in Dragon Boat Athletes - An Analysis of Changes in Blood Count Parameters Under Sport-specific Stress
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 40
- 主要终点
- change from Baseline in prohepcidin after performing dragonboating
研究概览
简要总结
The purpose of the study is:
- To investigate the effect of sport-specific stress in the iron metabolism of dragon boat athletes
- To investigate the effects of sport-specific stress in the activity of pro-hepcidin and hepcidin
详细描述
This investigation evaluates the effects of sport-specific stress in iron metabolism of dragon boat athletes. Recent studies showed a significant increase in hepcidin activity under exercise (Röcker L. et al.(2005): Iron regulatory protein hepcidin is increased in female athletes after a marathon. European Journal of Applied Physiology, S. 95, 569-571)which possibly influences the iron metabolism.
In particular in this investigation the activity of pro-hepcidin and hepcidin under sport-specific stress is analysed. Therefore elite dragonboat athletes will be included to this study. Every athlete is tested once. At one exercise day from every athlete the iron metabolism especially the change of hepcidin, prohepcidin and iron before and after a specific dragonboat intervention is analysed.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Single Group
- 主要目的
- Diagnostic
- 盲法
- Single (Investigator)
入排标准
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •athletes performing dragon boat sport
排除标准
- •acute clinically significant intercurrent diseases
结局指标
主要结局
change from Baseline in prohepcidin after performing dragonboating
时间窗: pre and post exercise intervention at the same day
one meassurement of prohepcidin immediate before and within three hours after performing two to four specific dragonboat interventions at the same day
次要结局
- haematocrit(pre and post exercise intervention at the same day)
- value of reticulocytes(pre exercise)
- value of hypochromic erythrocytes(pre exercise)
- change from Baseline in serum iron after performing dragonboating(pre and post exercise intervention at the same day)
- value of transferrin(pre exercise)
- value of transferrin saturation(pre exercise)
- value of ferritin(pre exercise)
- change from Baseline in hepcidin after performing dragonboating(pre and post exercise intervention at the same day)
研究者
Andree Hillebrecht
Dr.med.
University of Giessen