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Clinical Trials/NCT06654232
NCT06654232
Completed
Not Applicable

Patient-Reported Quality of Life in Patients With an Implantable-Cardioverter Defibrillator - A Cross-Sectional Observational Study

Universitaire Ziekenhuizen KU Leuven1 site in 1 country731 target enrollmentNovember 1, 2024

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Implantable Cardioverter Defibrillator (ICD)
Sponsor
Universitaire Ziekenhuizen KU Leuven
Enrollment
731
Locations
1
Primary Endpoint
ICD acceptance assessed using the Florida Patient Acceptance Survey (FPAS)
Status
Completed
Last Updated
5 months ago

Overview

Brief Summary

Patients at risk for life-threatening arrhythmias are eligible for the implantation of an implantable cardioverter-defibrillator (ICD), which has repeatedly shown improved survival. However, living with an ICD may pose several challenges and affect quality of life (QoL). This prospective cross-sectional observational cohort studies will provide detailed insights in patient-reported QoL. The aim is to study the QoL perspective of patients who have an ICD, including physical and emotional health; ICD acceptance; concerns of ICD patients with regard to physical and sexual activity.

Registry
clinicaltrials.gov
Start Date
November 1, 2024
End Date
October 31, 2025
Last Updated
5 months ago
Study Type
Observational
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Age ≥ 18 years of age
  • Patients with any type of ICD followed in UZ Leuven
  • Willing and able to provide signed written informed consent

Exclusion Criteria

  • Patients who are hospitalized
  • Patients with a mental disability
  • Patients already included in another interventional study

Outcomes

Primary Outcomes

ICD acceptance assessed using the Florida Patient Acceptance Survey (FPAS)

Time Frame: Cross-sectional at time of inclusion

The primary endpoint of the cross-sectional QoL-ICD study is the ICD acceptance assessed using the Florida Patient Acceptance Survey (FPAS). The FPAS began as a self-report survey with 47 items composed with the help of experts on psychosocial functioning in device patients, an expert in the field of psychometrics, and a cardiac electrophysiologist.2 Information obtained through surveys and interviews were used as guidelines for item construction. The result is an 18 question survey. Of these 18 questions, there are 3 filler items which are still relevant for ICD patients and the remaining questions cover 4 domains: (1) Return to Function; (2) Device-Related Distress; (3) Positive Appraisal; and (4) Body Image Concerns. Items are rated on a 5-point scale from 1 (strongly disagree) to 5 (strongly agree). Scale scores were calculated for each of the factors. By combining the scores for each question, a total FPAS score can be calculated.

Secondary Outcomes

  • - General QoL, including physical and emotional components, assessed using the Short Form Health Survey (SF-12)(Cross-sectional at time of inclusion)
  • - Cardiac-specific QoL assessed using the Kansas City Cardiomyopathy Questionnaire (KCCQ-12).(Cross-sectional at time of inclusion)
  • Florida Shock Acceptance score (FSAS)(Cross-sectional at time of inclusion)
  • Steinke Sexual Concerns Inventory(Cross-sectional at time of inclusion)
  • "Concept of a Good Death" questionnaire(Cross-sectional at time of inclusion)

Study Sites (1)

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