DRKS00013218招募中不适用
3D 2HG mapping as biomarker for IDH-mutation in glioma - KLI 646
适应症
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 90
研究概览
简要总结
FID-based 7T MRSI could not stably detect 2HG in gliomas. Indirect IDH determination based on the detectable metabolic profile seems possible and a publication is in progress as of May 2023.
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18 Years 至 one（—）
- 性别
- All
入选标准
- •WHO grade II and III glioma according to the updated 2016 WHO classification and a Karnofsky performance status =60%
排除标准
- •contraindications for MR imaging (claustrophobia, metal implants…), pregnancy
研究者
相似试验
已完成
不适用
Non Invasive IDentification of Gliomas With IDH1 MutationNon Invasive Diagnosis of GliomaNCT01703962Institut National de la Santé Et de la Recherche Médicale, France6
Unknown
不适用
Non Invasive Detection of IDH1/2 Mutation in GliomasIDH1/IDH2 MutationGliomaNCT02597335Assistance Publique - Hôpitaux de Paris40
已完成
3 期
IDH mutated 1p/19q intact lower grade glioma following resection: Wait Or Treat? IWOT - A phase III studyNL-OMON48284European Organisation for Research in Treatment of Cancer (EORTC)127
进行中（未招募）
1 期
Treatment of IDH mutated, 1p/19q lower malignant grade glioma of the brain after surgery: Wait with further treatment or start Treatment immediately : I-WOTHistologically WHO grade II (diffuse) or III (anaplastic) astrocytoma, IDHmt without 1p/19q co-deletion (local diagnosis)MedDRA version: 20.0Level: PTClassification code 10065869Term: Astrocytoma, low gradeSystem Organ Class: 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)MedDRA version: 20.0Level: PTClassification code 10002224Term: Anaplastic astrocytomaSystem Organ Class: 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)EUCTR2018-003539-31-NOEuropean Organisation for Research and Treatment of Cancer624
进行中（未招募）
1 期
Treatment of IDH mutated, 1p/19q lower malignant grade glioma of the brain after surgery: Wait with further treatment or start Treatment immediately : I-WOTHistologically WHO grade II (diffuse) or III (anaplastic) astrocytoma, IDHmt without 1p/19q co-deletion (local diagnosis)MedDRA version: 20.0Level: PTClassification code 10065869Term: Astrocytoma, low gradeSystem Organ Class: 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)MedDRA version: 20.0Level: PTClassification code 10002224Term: Anaplastic astrocytomaSystem Organ Class: 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)EUCTR2018-003539-31-NLEuropean Organisation for Research and Treatment of Cancer624