Evaluation of molecular sputum test diagnostic for lung cancer

Completed

• Conditions: bronchus carcinoma; lung cancer; 10029107

• Registration Number: NL-OMON38180
• Lead Sponsor: Vrije Universiteit Medisch Centrum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 18 June 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 600

Inclusion Criteria

patients suspicious of lung cancer;
Patients with progression of lung cancer after treatment

Exclusion Criteria

No

Study & Design

• Study Type: Observational non invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Primary research variables<br /><br>A) Establish effect of prolonged sputum sampling on sensitivity for diagnosis<br /><br>of lung cancer.<br /><br>B) Establish clinical sensitivity and specificity of molecular sputum test for<br /><br>the diagnosis of lung cancer in symptomatic patients, and comparison of<br /><br>molecular test with cytological examination.<br /><br>C) Establish clinical sensitivity and specificity of molecular sputum test for<br /><br>early diagnosis of lung cancer</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>A) Establish in subpopulation analysis of exhaled air.<br /><br><br /><br>B) Establish in subpopulation analysis molecular markers in blood for<br /><br>comparison with sputum.</p><br>