Prevalence and Serotype Distribution of Streptococcus Pneumoniae in Healthy Vietnamese Children From 6 Months to 5 Years Old
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 800
- 试验地点
- 3
- 主要终点
- Prevalence of pneumococcal carriage in the nasopharynx in children from 6 months to 5 years old in the Vietnamese community
研究概览
简要总结
This observational study is designed as a cross-sectional survey of children from 6 months and 5 years old who visit the Vietnam Vaccination Center (VNVC) system in Hanoi, Danang and Ho Chi Minh City for vaccination services.
After getting the informed consent form from a parent/guardian for their child(s) to participate in the study, nasopharyngeal swab sample will be taken. His/her guardian will be interviewed face-to-face with information related to epidemiological characteristics, nutritional status, child's birth history, hospitalization history, vaccination history, recent antibiotic usage, breastfeeding time, and environmental and lifestyle factors.
The goal is to document the burden and risk factors of pneumococcal infections in the community of healthy Vietnamese children. The main questions it aims to answer are:
- What is the prevalence of pneumococcus in healthy children?
- What is the distribution of pneumococcus serotypes in the community of healthy Vietnamese children?
- What are risk factors of pneumococcus infection in the community of healthy Vietnamese children?
研究设计
- 研究类型
- Observational
- 观察模型
- Ecologic Or Community
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 6 Months 至 5 Years（Child）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Children between 6 months and 5 years
排除标准
- •Children with chronic diseases (including immunologic diseases, neoplastic disorders, renal, cardiac, hepatic, or hematologic diseases, broncho dysplasia, Down syndrome, chronic otitis media with effusion)
- •Children with acute/chronic upper or lower respiratory tract infection
- •Children have used antibiotics within 1 week prior to entering the study
研究组 & 干预措施
Children between 6 months and 5 years
结局指标
主要结局
Prevalence of pneumococcal carriage in the nasopharynx in children from 6 months to 5 years old in the Vietnamese community
时间窗: Day 0 after recruitment
Pneumococcal prevalence in children by age group, sex and geographical area
Serotype distribution of pneumococcal strains in Vietnamese children from 6 months to 5 years old in the community
时间窗: Day 0 after recruitment
The number of carrier individuals by serotype will be determined for age group, sex and geographical area
次要结局
- Risk factors associated with pneumococcal carriage(Day 0 after recruitment)