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Obstructive Sleep Apnea Syndrome: Evaluation of the Efficacy of Sleepinnov© (Spiri+) Continuous Positive Airway Pressure Device

Not Applicable
Completed
Conditions
Obstructive Sleep Apnea Syndrome
Interventions
Device: Spiri+
Registration Number
NCT04141176
Lead Sponsor
Sleepinnov Technology
Brief Summary

Continuous Positive Airway Pressure (CPAP) is the reference treatment of patients suffering from Obstructive Sleep Apnea Syndrome (OSAS).This device functions as a pneumatic stent that stabilizes the upper airway, prevents periodic collapses during sleep.The correction of abnormal respiratory events during sleep allows improvement of symptoms related to OSAS and restores quality of life.The purpose of this study is to validate the efficacy of a new CPAP brand developed by Sleepinnov©.

Detailed Description

Obstructive sleep apnea syndrome (OSAS) is characterized by the repetitive occurrence of partial or complete pharyngeal obstructions during sleep.Continuous Positive Airway Pressure (CPAP) is the first line treatment of OSAS.

The aim of the prospective monocentric two steps pilot study SPIRI+ is to validate the efficacy of a new CPAP brand developed by Sleepinnov©.

* the first step will validate the capability of the algorithm to appropriately detect of abnormal repiratory events during sleep.the metrics will be a comparison of the total number of events detected by the CPAP Sleepinnov© with data arising from a concurrent polysomnography.

* the second step will check overall clinical efficacy of the new CPAP device by assessing the percentage of OSAS with an index of residual events below 10 and 5 per hour.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
20
Inclusion Criteria
  • newly diagnosed and untreated Obstructive sleep apnea syndrome (IAH >15/hour) with an indication of treatment with CPAP
  • Patients who have given their informed written consent
Exclusion Criteria
  • Pregnant or lactating women
  • Patients not affiliated to the French social security system or equivalent
  • Patient deprived of liberty by judicial or administrative decision
  • Patients under guardianship or curatorship

Study & Design

Study Type
INTERVENTIONAL
Study Design
SINGLE_GROUP
Arm && Interventions
GroupInterventionDescription
Spiri+Spiri+new CPAP device
Primary Outcome Measures
NameTimeMethod
Part 1: Validation of algorithm detection of respiratory eventsbaseline

Comparison of the total number of events detected by the CPAP Sleepinnov© with data arising from a concurrent polysomnography.

Part 2: Validation of overall clinical efficacybaseline

Percentage of OSAS with an index of residual events below 10 and 5 per hour

Secondary Outcome Measures
NameTimeMethod
Part 1:baseline

Compare the different types of events detected by the Spiri + CPAP algorithm to the concomitant respective indices scored during concurrent

Trial Locations

Locations (1)

University Hospital Grenoble

🇫🇷

La Tronche, France

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