The Effect of Prophylactic Hemodialysis on the Morbidity and Mortality of the Patients With Chronic Kidney Disease Stages 3-4 Undergoing Coronary Artery Graft Bypass
试验速览
- 阶段
- 2 期
- 发起方
- 入组人数
- 120
- 试验地点
- 2
- 主要终点
- morbidity
研究概览
简要总结
Coronary artery disease is a major cause of death in patients with renal dysfunction Among patients who undergo coronary artery bypass grafting ,renal dysfunction is known To be a major predictor of in-hospital and remote mortality As little is known about the impact of non-dialysis-dependent renal dysfunction on short and mid term Outcomes following coronary surgery we have decided to investigate the effect of prophylactic Hemodialysis on the mortality and morbidity of the patients with ckd (stage 3,4 ) and compare these Effect with the control group
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •* ckd patients with stage 3,4
- •* CABG for the first time
排除标准
- •previous CABG (coronary artery bypass grafting)
- •AKI(acute kidney injury)
- •dialysis patients
结局指标
主要结局
morbidity
时间窗: the morbidity during the time of hospitalization until discharge (baseline) and six month later
morbidity is defined as length of hospitalization,infection rate,duration of mechanical ventilation,bleeding complications,
次要结局
- mortality(from the time of CABG (baseline) until six months later)
研究者
Mohammad Reza Khatami
Member of research board of Nephrology ResearchCenter of Tehran University of Medical Sciences
Imam Khomeini Hospital