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临床试验/NCT07247435
NCT07247435尚未招募不适用

Role of Computed Tomography in Diagnosis of Syndromic and Non Syndromic Tetralogy of Fallot

Assiut University0 个研究点目标入组 37 人开始时间: 2025年11月15日最近更新:

试验速览

阶段
不适用
状态
尚未招募
入组人数
37
主要终点
Anatomical anomalies identification

研究概览

简要总结

To evaluate the role of MSCT in diagnosis and surgical planning in tetralogy of Fallot cases.

详细描述

Role of Computed tomography (CT) : CT has become an indispensable imaging modality in the comprehensive evaluation and management of Tetralogy of Fallot (ToF). While echocardiography remains the initial diagnostic tool, CT offers unparalleled spatial resolution and the ability to generate high-quality, three-dimensional reconstructions of both intracardiac and extracardiac anatomy. This is particularly valuable for identifying associated anomalies such as major aortopulmonary collateral arteries (MAPCAs), anomalous coronary artery origins, and variations in pulmonary artery branching patterns that can significantly influence surgical decision-making. Preoperatively, CT enables precise assessment of the severity and extent of right ventricular outflow tract obstruction, ventricular septal defect morphology, and the relationship of the overriding aorta to the interventricular septum.

Overall, CT complements other imaging modalities by providing a fast, accurate, and comprehensive anatomical roadmap that guides surgical planning, informs long-term follow-up, and aids in the early detection of complications. Its role is particularly pronounced in complex and syndromic cases of ToF, where anatomical variations are more common and precise preoperative mapping is critical for successful outcomes.

研究设计

研究类型
Observational
观察模型
Case Only
时间视角
Prospective

入排标准

年龄范围
— 至 12 Years(Child)
性别
All
接受健康志愿者

入选标准

  • - patients aged 1 day up to 12 years Confirmed diagnosis of tetralogy of Fallot. Patients with tetralogy of Fallot as apart from genetic syndrome.

排除标准

  • Patients with other isolated congenital heart anomalies Previously operated cases of tetralogy of Fallot.

结局指标

主要结局

Anatomical anomalies identification

时间窗: 3 years

Identification cardiac and extra-cardiac anatomical anomalies

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Benyamin Adel Abdullah Gaballah

RD

Assiut University

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