The effect of Conjugated linoleic acids on some bone markers, in adult with active rheumatoid arthritis
Phase 1
- Conditions
- Rheumatoid Arthritis.Rheumatoid arthritis, unspecified
- Registration Number
- IRCT201403029472N5
- Lead Sponsor
- Vice-chancellor for Research, Tehran University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 46
Inclusion Criteria
person with RA diseases as ACR criteria, having RA from 2 years ago; age between 18-69 years; not being pregnant or lactated; not smoking and drink alcohol; haven’t eaten multivitamin or antioxidants supplements from 3 month ago; don't eat lowering blood pressure; don't eat anti pregnancy drugs, exclusion criteria: Changes in diet or physical activity every day; taking less than 80% of supplements given to patients at baseline(the compliance lower than %80); consumption of contraceptives, multivitamins and antioxidant supplements; renal , hepatic , thyroid, parathyroid diseases, cancer, heart. diseases.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Telopeptide C. Timepoint: Before and after the study. Method of measurement: Bleeding and measurment with ELISA.;Osteocalcine. Timepoint: Before and after the study. Method of measurement: Bleeding and measurment with ELISA.;Serum PTH. Timepoint: Before and after the study. Method of measurement: Bleeding and measurment with ELISA.;Serum Calcium. Timepoint: Before and After the study. Method of measurement: Bleeding and measurment with HPLC.
- Secondary Outcome Measures
Name Time Method said usage. Timepoint: Before and after study. Method of measurement: Questionnair.;BMI. Timepoint: Before and after study. Method of measurement: Formula.