Third Molars Extraction and Periodontal Disease

Recruiting

• Conditions: Periodontal Diseases
• Interventions: Procedure: Tooth extraction

• Registration Number: NCT06520137
• Lead Sponsor: Azienda Ospedaliera Universitaria Senese

Brief Summary

The aim of the study is to evaluate the changes in periodontal conditions on the distal aspect of the second maxillary molar after the extraction of the maxillary wisdom tooth. As secondary outcome patient- related and tooth-related factors will be analysed to evaluate their effects on the periodontal varibales during time.

Detailed Description

Not available

Study Timeline

• Study Start: 2024-03-27
• Status Verified: 2024-07
• Study First Submitted: 2024-07-20
• Study First Submitted QC: 2024-07-24
• Last Update Submitted: 2024-07-24
• Study First Posted: 2024-07-25
• Last Update Posted: 2024-07-25
• Primary Completion: 2026-03-27
• Study Completion: 2026-09-15

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 126

Inclusion Criteria

• Age more than 18 years or older
• Presence of an impacted upper wisdom tooth that need to undergo surgical extraction
• Participants need to be able to sign and understand the informed consent and to follow the study-related procedures.

Exclusion Criteria

• People that have compromised general health conditions (ASA 3, 4, 5, 6)
• Patients that assumed antibiotics in the last 6 months
• Pregnant or breastfeeding women
• Patients who suffer from periodontitis stage III and IV
• Presence of a third molar with incomplete root formation is not taken into account for the surgical extraction.
• Smoker patients

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Group A with PPD ≤ 3 mm	Tooth extraction	-
Group B with PPD ≥ 4 mm	Tooth extraction	-

Primary Outcome Measures

Name	Time	Method
Bone Level (BL)	Baseline, 1 month, 6 months, 12 months, 24 months	Distance between the bone crest and the cemento-enamel junction (CEJ)
Probing Pockeet Depth (PPD)	Baseline, 1 month, 6 months, 12 months, 24 months	Distance between the free gingival margin and the apical location of the probe's tip.

Secondary Outcome Measures

Name	Time	Method
Keratinized Tissue (KT)	Baseline, 1 month, 6 months, 12 months, 24 months	Distance between the muco-gingival line and the free gingival margin
Clinical Attachment Level (CAL)	Baseline, 1 month, 6 months, 12 months, 24 months	Distance between the cemento-enamel junction and the apical location of the probe's tip
Type of impaction	Baseline	According to Archer's classification it is possible to have seven types of impaction: mesio-angular, disto-angular, bucco-angular, linguo-angular, horizontal, vertical, inverted.
Recession (REC)	Baseline, 1 month, 6 months, 12 months, 24 months	Distance between the free gingival margine and the cemento-enamel junction (CEJ)

Trial Locations

Locations (1)

University of Siena; 🇮🇹 Siena, Italy/SI, Italy