MRI in the fast lane: MR-STAT

Completed

Conditions: Overige zenuwstelsel-aandoeningen: demyeliniserende aandoeningen (MS), neoplasmata en epilepsie
Stroke
ischemic infarct
10007963

Registration Number: NL-OMON48176

Lead Sponsor: niversitair Medisch Centrum Utrecht

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Completed

Sex: Not specified

Target Recruitment: 50

Inclusion Criteria

In order to be eligible to participate in this study, a patient must meet the
following criteria:
• Age >= 18 years
• Diagnosed with one of the following neurological diseases: primary brain
tumor, epilepsy, MS or ischemic stroke
• Previous imaging findings characteristic of particular neurological disease
• Ability to lie supine in the MRI scanner for 45 minutesAlthough not an
inclusion criterion, care is taken to select those patients that are already
scheduled for a standard clinical follow-up MRI examination within the next 4
months, thereby limiting patient burden by providing the option to combine both
study- and clinical MRI examination on the same day.Inclusion criteria for
healthy volunteers are the following:
• Age >= 18 years
• No history of neurological diseases

Exclusion Criteria

Patients will be excluded when meeting one of the following criteria:
• Atypical imaging findings not characteristic for the neurological
diagnosisExclusion criteria for the healthy volunteers are as follows:
• History of any neurological disease

Study & Design

Study Type: Observational invasive

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The main study parameter will be the image quality scores of the<br /><br>MR-STAT-generated image data sets with regard to overall image quality, image<br /><br>artifacts, and visualization of several predefined anatomical structures; these<br /><br>scores will be compared with those of the standard MRI data sets.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>The secondary study parameter will be the image quality of the<br /><br>MR-STAT-generated image data sets compared with the standard MRI data sets,<br /><br>assessed in a side-by-side fashion.</p><br>