NL-OMON44604CompletedPhase 2
Evaluation of 18F-AV-1451 kinetic modeling in patients in Alzheimer's disease and healthy controls - Tau-Image
Avid Radiopharmaceuticals0 sites20 target enrollmentStarted: TBDLast updated:
Conditions
Trial Snapshot
- Phase
- Phase 2
- Status
- Completed
- Sponsor
- Enrollment
- 20
Study Overview
Brief Summary
No summary available.
Study Design
- Study Type
- Interventional
Eligibility Criteria
- Ages
- 18 to 99 (—)
Inclusion Criteria
- •Healthy Control Subjects:
- •1. Male or female * 50 years of age
- •2. No evidence of cognitive impairment;AD subjects:
- •1. Male or female * 50 years of age
- •2. Clinical diagnosis of probable Alzheimer's Disease (AD)
- •3. MMSE * 18
- •4. PET or CSF biomarker data supports that the subject is amyloid positive
Exclusion Criteria
- •All subjects:
- •1. Current clinically significant psychiatric condition
- •2. Normal hemoglobin * 8 in males or * 7 in females
- •3. Possible pregnancy
- •4. MRI evidence of brain structural abnormality
- •5. Relevant history of drug allergy or hypersensivity
- •6. Current clinically significant cardiovascular disease, abnormalities on screening ECG (e.g. QTc >450msec)
- •7. Donated blood <6 months
Investigators
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