on-invasive glycocalyx measurements in premature atherosclerosis.

niversity of Maastricht, research institute CARIM0 个研究点目标入组 40 人开始时间: 待定最近更新: 2024年2月28日

试验速览

•Cases: Male and female.
•Subjects should have premature cardiovascular disease, which will be defined as cardiac, cerebral or peripheral vascular disease before the age of 40 years. Since a diminished glycocalyx volume is viewed as one of the first vascular alterations before overt atherosclerosis develops, we believe it is of no concern when the cardiovascular event had occurred. Furthermore, all of these subjects must have a positive family history for cardiovascular disease. This will be defined as at least one first degree or two or more second degree family members with cardiovascular disease before the age of 55 for men and before the age of 60 for women.

•Patients will be excluded if they have a positive history for hypertension, diabetes mellitus or other disease and in case of pregnancy or lactating women, if subjects are below the age of 18 years, or if subjects are unable to give informed consent.

发起方

niversity of Maastricht, research institute CARIM