Age related trends of serum Anti-Mullerain Hormone (AMH) and Antral Follicular Count (AFC) in Indian Infertile Women
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 5,000
- 试验地点
- 1
- 主要终点
- Ovarian Reserve
研究概览
简要总结
SUMMARY
The introduction of AMH and AFC in Reproductive Endocrinology is considered a revolution in the prediction of ovarian reserve for individualizing treatment and counsel the couple regarding successful treatment. AMH is produced by granulosa cells, so serum AMH levels gradually decreases with advancing age due to reduction of the number of antral follicles. Serum AMH measurements are less dependent on operators and do not have intra and inter cycle variation. AFC is also a good predictor of ovarian response. AFC has the closest association with chronological age in normal and infertile Indian women. Present study will provide relationship between age and AMH & AFC.
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 20.00 Year(s) 至 44.00 Year(s)（—）
- 性别
- Female
入选标准
- •Age between 20-44 years 2) BMI 18 to 30 3) Presence of both ovaries.
排除标准
- •Pituitary / Adrenal disorders 2) Malignancy 3) PCOS 4) Proven Tuberculosis 5) Smoking 6) History of chemotherapy or radiotherapy 7) Ovarian surgery in the past 3 months.
结局指标
主要结局
Ovarian Reserve
时间窗: Cross sectional study, only once sample will be collected from infertile women
次要结局
- AMH and AFC(Cross sectional study, only once sample will be collected from infertile women)