68Ga-FAPI-46 and 18F-FDG PET/CT for evaluation of head and neck squamous cell carcinoma: a comparative analysis

Completed

• Conditions: Detection of primary cancer and metastatic lesions in patients with HNSCC.; Head and Neck Neoplasms; 68Ga-FAPI

• Registration Number: TCTR20210902003
• Lead Sponsor: ational Cyclotron and PET Centre, Chulabhorn Hospital

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Completion: 2021-05-25
• Study Start: 2021-09-02
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

1. Patients with pathologically confirmed HNSCC
2. Patients who were > 18 years old
3. Patients who were scheduled for PET/CT with indication for initial staging or suspected recurrence

Exclusion Criteria

1. Patients with fasting blood sugar > 150 mg/dL
2. Patients with GFR < 45ml/min
3. Patients with second primary tumor except HNSCC
4. Patients who were pregnant or breast feeding

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Concordance of FAPI and FDG PET/CT at the time of intervention (PET/CT interpretation) Concordant rate

Secondary Outcome Measures

Name	Time	Method
Detection of primary and metastatic tumor at the time of intervention (PET/CT interpretation) Detection rate,Diagnostic accuracy at the time of intervention (PET/CT interpretation) Sensitivity, specificity, accuracy