The efficacy of collagenated xenogenic block bone (A-Oss collagen) in peri-implantitis regenerative surgery compared with particulate xenogenic bone: A single-center, single-blind, randomized controlled trial.

Seoul National University Dental Hospital0 个研究点目标入组 50 人开始时间: 待定最近更新: 2024年7月23日

适应症

试验速览

暂无简介。

•1. Subjects whose general condition is eligible for surgical treatment of peri-implantitis.
•2. Subjects who have undergone nonsurgical treatment of peri-implantitis within the last 3 months, but the lesion has not been resolved.
•3. Implant prosthesis can be removed.
•4. Subjects with intrabony defects around implants on radiographs.
•5. peri-implant bone loss on radiograph: 6 mm or less on radiographs.
•6. Subjects who voluntarily consent to the clinical trial and are willing to comply with the protocol

•1. Acute infection at the site where peri-implantitis is present.
•2. Extensive bone loss due to peri-implantitis and/or periodontitis that requires extraction of adjacent teeth.
•3. Pregnant or lactating women.
•4. Uncontrolled metabolic systemic disease (hypertension, diabetes).
•5. A history of radiation therapy and chemotherapy in the head and neck area.
•6. Complications of serious cardiovascular disease, respiratory system disease, kidney disease, liver disease, digestive system disease, blood system disease, and neuropsychiatric disease.
•7. A history of severe drug allergy.
•8. Subjects receiving long-term systemic steroid therapy.
•9. Subjects with ASA classification III, IV, V, VI.
•10. Surgical treatment was not recommended by a physician due to the risk of medication-related osteonecrosis of the jaw (MRONJ).
•11. Subject is inappropriate for participating in the research due to ethical issues.

发起方