Comparison of conventional vs multimodal analgesia in attenuation of stress response to carboperitoneum and post operative analgesia in laparoscopic abdominal surgeries
试验速览
- 阶段
- 2 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 108
- 试验地点
- 1
- 主要终点
- To observe and compare the effect of conventional and multimodal analgesia in attenuation of haemodynamic stress response to carboperitoneum in laparoscopic abdominal surgery.
研究概览
简要总结
multimodal analgesic strategies have caused major improvements in pain management with increased efficacy and better tolerability along with opoid sparing effect.in our study we intend to study if multimodal analgesia is more beneficial compared to conventional analgesia in attenuation of stress response to carboperitoneum and post operative analgesia.
Null hypothesis- iIn laparoscopic abdominal surgeries, there is no difference between multimodal and conventional analgesia in reduction of stress response to carboperitoneum and post operative analgesia.
研究设计
- 研究类型
- Interventional
- 分配方式
- Computer generated randomization
- 盲法
- Participant and Outcome Assessor Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 65.00 Year(s)（—）
- 性别
- All
入选标准
- •patients undergoing laparoscopic abdominal surgeries 2)ASA grade 1 and 2 3)laparoscopic abdominal surgeries more than 30min to less than 3hours.
排除标准
- •patient refusal 2)known or suspected allergy to any of the drugs used.
- •psychiatric illness.
结局指标
主要结局
To observe and compare the effect of conventional and multimodal analgesia in attenuation of haemodynamic stress response to carboperitoneum in laparoscopic abdominal surgery.
时间窗: The haemodynamic stress response. The haemodynamic parameters(HR,SBP,DBP,MAP,ETCO2) will be studied at baseline value, after completion of the study analgesic solution , immediately after intubation, before carboperitoneum and immediately after carboperitoneum, at 5min,10min,20min,30min and every 30min upto the end of carboperitoneum.
次要结局
- To observe and compare the effect of conventional and multimodal analgesia in post operative pain relief in laparoscopic abdominal surgeries.(Postoperative analgesia will be assessed using the VAS score at 5min,15min,2hrs,4hrs and 6hrs.)