Effect of Brazil Nut Consumption in the Microvascular Endothelial Function, Oxidative Stress and Metabolic Abnormalities in Hypertensive and Dyslipidemic Subjects
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 125
- 主要终点
- Antioxidant biomarker
研究概览
简要总结
The purpose this research is to check the effect of Brazil Nuts consumption in oxidative stress, metabolic abnormalities and microvascular endothelial function dyslipidemic and hypertensive patients.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Treatment
- 盲法
- Triple (Participant, Care Provider, Investigator)
入排标准
- 年龄范围
- 20 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •adults > 20 years old
- •Dyslipidemic
- •Hypertensive
排除标准
- •Allergy to nuts
- •Consumption of nuts or vitamins/minerals supplement
- •Loss weight before the research
- •pregnancy
- •Kidney chronic disease
研究组 & 干预措施
Cassava flavored flour
The placebo group (cassava flour flavored) received 9g/day of cassava flour flavored during three months (12 weeks)
干预措施: Brazil nut flour (Dietary Supplement)
Brazil nut flour
The Brazil nut group received 13g/day of Brazil nut flour during three months (12 weeks)
干预措施: Placebo (cassava flavored flour) (Dietary Supplement)
结局指标
主要结局
Antioxidant biomarker
时间窗: Change from Baseline at 12 weeks.
Change from Baseline plasma Gluthathione Peroxidase activity (nmol/min/ml) at 12 weeks, samples were stocked at -80 degrees.
次要结局
- Oxidative stress biomarker(Change from Baseline at 12 weeks.)
- microvascular endothelial function(Change from baseline at 12 weeks)
研究者
Grazielle Vilas Boas Huguenin
Mrs
Universidade Federal do Rio de Janeiro