ISRCTN35143689已完成不适用
Candesartan in renal artery stenosis (CARLAS)
AstraZeneca (Sweden)0 个研究点目标入组 200 人开始时间: 2007年12月18日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 200
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 性别
- All
入选标准
- •1. Blood pressure above 140 mmHg/90 mmHg
- •2. Confirmation of renal artery stenosis by either duplex ultrasonography, CT-angiography or MR-angiography
排除标准
- •1. Renal size <7.5 cm at the stenotic side
- •2. Age >80 years
- •3. Pregnancy or nursing mother
- •4. Terminal renal failure (Glomerular Filtration Rate [GFR] <15 ml/min)
- •5. Treatment with Angiotensin-Converting Enzyme (ACE) inhibitors or angiotensin receptor blockers
- •6. Renovascular hypertension of other etiology than atherosclerosis or Flow-Mediated Dilation (FMD)
- •7. Chronic glomerular disease with urinary albumin excretion (in mg/24h) (tU-alb) >1g/day
- •8. Diabetic nephropathy with tU-alb >0.3 g/day
- •9. Contraindication for renal angiography/PTRA (eg. serious contrast allergy)
- •10. Other forms of secondary hypertension
- •11. Serious malignant disease
- •12. Treatment with immune-modulating medications eg. cyclosporin and oral steroids
研究者
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