MedPath

ovel Identified complement regulatory functions of physiological proteins: Mechanisms, physiological relevance and potential for therapeutic applications

Recruiting
Conditions
C3 glomerulonephritis
N05
Unspecified nephritic syndrome
Registration Number
DRKS00025182
Lead Sponsor
Medical Center - University of Freiburg, Renal Division, Department of Medicine
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
All
Target Recruitment
30
Inclusion Criteria

Patients with the following diagnoses: typical, atypical hemolytic uremic syndrome, thrombotic thrombocytopenic purpura, C3 gloerulopathy, IgA nephritis, Schoenlein-Hennoch purpura nephritis or ANCA vasculitis and healthy controls.

Exclusion Criteria

missing consent to biomaterial database

Study & Design

Study Type
observational
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
The protein studied shows measurable complement regulation or complement activation on patient samples.
Secondary Outcome Measures
NameTimeMethod
Influence of the investigated protein on the pathomechanism
© Copyright 2025. All Rights Reserved by MedPath