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临床试验/NCT05802355
NCT05802355已完成不适用

Manual Diaphragmatic Release: Is It Helpful for Cleaning-laborers With Work-related Respiratory Hazards in Overcoming the Upsetting Respiratory Symptoms, Boosting Immune Response, and Enhancing Functional Ability?

Maged Basha2 个研究点 分布在 1 个国家目标入组 36 人开始时间: 2022年3月10日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
36
试验地点
2
主要终点
Forced vital capacity

研究概览

简要总结

This study intended to examine the effect of manual diaphragm release on pulmonary function, chest wall mobility, and functional ability in female occupational cleaners with respiratory hazards.

详细描述

Cleaning chores have been linked to exposure to various chemical agents that have the potential to cause harmful effects on both the respiratory system and cardiovascular markers, many cleaning products and disinfectants contain ingredients that can act as airway irritants. One of the physical therapy procedures that is used to manage chest disorders is manual diaphragm release which aims to lengthen the diaphragm musculature whereas encouraging better and more proficient contraction.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Treatment
盲法
Single (Outcomes Assessor)

入排标准

年龄范围
35 Years 至 45 Years(Adult)
性别
Female
接受健康志愿者

入选标准

  • Female occupational cleaners.
  • Age between 35 and
  • Had work-related respiratory hazards.
  • Clinically stable.
  • No exacerbation in the previous 6 weeks.
  • Working in an occupation with respiratory hazards for at least 2 years.
  • Mild to moderate air way obstruction.
  • Willingness to participate in this study and provide a consent form.

排除标准

  • Other cardiopulmonary diseases.
  • Body mass index > 30 kg/ m
  • Previous thoracic or abdominal surgery.
  • Smokers and users of tobacco in any form (chewing, snuffing or water pipe).
  • Systemic conditions (e.g., diabetes mellitus, hypertension).
  • Sever airway obstructions.
  • Inability to perform the required exercises.
  • Inability to attend the scheduled sessions.

结局指标

主要结局

Forced vital capacity

时间窗: after 12 weeks

measured using a portable MicroLab spirometer (Vyaire Medical, Mettawa, Illinois) in accordance with current lung function testing standards

Serum IgE

时间窗: after 12 weeks

The Organon Teknika Microwell system (Organon Teknika Corp, Boxtel, the Netherlands) and an enzyme-linked immunosorbent test kits, were utilized to assess total serum IgE (IU/mL) at 450 nm.

Forced expiratory volume in one second

时间窗: after 12 weeks

measured using a portable MicroLab spirometer (Vyaire Medical, Mettawa, Illinois) in accordance with current lung function testing standards

pulmonary expiratory flow

时间窗: after 12 weeks

measured using a portable MicroLab spirometer (Vyaire Medical, Mettawa, Illinois) in accordance with current lung function testing standards

次要结局

  • Functional performance(after 12 weeks)
  • Chest wall mobility(after 12 weeks)

研究者

发起方
Maged Basha
申办方类型
Other
责任方
Sponsor Investigator
主要研究者

Maged Basha

Assistant Professor, College of Medical Rehabilitation, Qassim University

Qassim University

研究点 (2)

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