Electroacupuncture for Chemotherapy-induced Peripheral Neuropathy: A Randomized, Controlled Trial

Not Applicable

Recruiting

Conditions: Diseases of the nervous system

Registration Number: KCT0000506

Lead Sponsor: Korea Institute of Oriental Medicine

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Recruiting

Sex: All

Target Recruitment: 40

Inclusion Criteria

1. Males and females aged 18 years and older
2. Patients who had received or were currently receiving neurotoxic chemotherapy with a diagnosis of cancer
3. Symptoms of peripheral neuropathy of duration = 1 month attributed to chemotherapy, and a score = 4 out of 10 on the NRS scale.
4. No use of medications to prevent or treat neuropathy within 2 weeks or stable use had been made in their medications to prevent or treat neuropathy within 2 months before screening.
5. ECOG PS of 0-2
6. Life expectancy = 6 months
7. Agreed with written informed consent

Exclusion Criteria

1. Pre-existing or history of peripheral neuropathy due to any cause other than chemotherapy (diabetes, peripheral vascular disease, HIV, alcohol, toxin, hereditary, nerve compression injuries, etc.)
2.Known hypersensitivity reaction after acupuncture treatment or inability to cooperate with acupuncture procedure
3. Received acupuncture, moxibustion, cupping or herbal medicine for peripheral neuropathy last 4 weeks
4. Cardiovascular disorder (e.g. arrhythmia) or using pacemaker
5. Pregnant, expecting pregnant or nursing women
6. Those who are not willing to comply with this study protocol

Study & Design

Study Type: Interventional Study

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
EORTC QLQ-CIPN20

Secondary Outcome Measures

Name	Time	Method
11-point numerical rating scale (NRS) ;Semmes Weinstein monofilaments test;Nerve Conduction Study;EORTC QLQ-C30;Patient Global Impression of Change (PGIC) ;Adverse events