Perception of Cure Among Patients With Metastatic Cancer

Withdrawn

• Conditions: Hematopoietic and Lymphoid Cell Neoplasm; Metastatic Malignant Solid Neoplasm
• Interventions: Other: Electronic Medical Record; Other: Survey Administration

• Registration Number: NCT04820894
• Lead Sponsor: City of Hope Medical Center

Brief Summary

This study collects information about perception of cure among patients with cancer that has spread to other places in the body (metastatic). This study aims to determine patients' perception (knowledge) before starting immunotherapy and if differences exist in understanding of treatment to stimulate or restore the ability of the body's immune (defense) system to fight infection and disease (immunotherapy) based on social and economic factors or on race/ethnicity.

Detailed Description

PRIMARY OBJECTIVE:

I. To assess the proportion of patients with metastatic cancer who anticipate cure before starting immunotherapy.

SECONDARY OBJECTIVES:

I. To determine if expectations of cure are associated with quality of life and distress.

II. To determine if patients' perceptions differ by gender, age, and ethnicity.

OUTLINE:

Patients complete surveys over 30 minutes about sociodemographic information and perception of immunotherapy, over 10 minutes about expectations of cure, over 10 minutes about anxiety, over 10 minutes about depression, and over 30 minutes about physical well-being. Patients' medical records are reviewed.

Study Timeline

• Study First Submitted: 2021-03-25
• Study First Submitted QC: 2021-03-25
• Study First Posted: 2021-03-29
• Study Start: 2021-10-30
• Primary Completion: 2022-01-05
• Study Completion: 2022-01-05
• Status Verified: 2025-05
• Last Update Submitted: 2025-05-22
• Last Update Posted: 2025-05-23

Recruitment & Eligibility

• Status: WITHDRAWN
• Sex: All
• Target Recruitment: Not specified

Inclusion Criteria

Not provided

Exclusion Criteria

Not provided

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Observational (survey, medical records review)	Survey Administration	Patients complete surveys over 30 minutes about sociodemographic information and perception of immunotherapy, over 10 minutes about expectations of cure, over 10 minutes about anxiety, over 10 minutes about depression, and over 30 minutes about physical well-being. Patients' medical records are reviewed.
Observational (survey, medical records review)	Electronic Medical Record	Patients complete surveys over 30 minutes about sociodemographic information and perception of immunotherapy, over 10 minutes about expectations of cure, over 10 minutes about anxiety, over 10 minutes about depression, and over 30 minutes about physical well-being. Patients' medical records are reviewed.

Primary Outcome Measures

Name	Time	Method
Functional Assessment of Cancer Therapy-General (FACT-G)	Up to 2 years	Descriptive analyses (e.g. frequency statistics) will be used to characterize the sample and to look at the association between Functional Assessment of Cancer Therapy-General (FACT-G) overall score with perception of cure score.
Percentage of patients	Up to 2 years	Will assess the percentage of patients who anticipate cure before starting immunotherapy, scoring a '1' on the Perception of cure tool, and anticipate \>75% chance for a cure.
Perceptions of cure	Up to 2 years	Chi-square analyses will be used to examine perceptions of cure by sociodemographic characteristics: gender (male and female), age (\< 60 and \> 60), and ethnicity (white non-Hispanic, Hispanic, and other).
Patient Reported Outcomes Measurement Information System (PROMIS)	Up to 2 years	Descriptive analyses (e.g. frequency statistics) will be used to characterize the sample and to look at the association between Patient Reported Outcomes Measurement Information System (PROMIS) tool score with perception of cure score.

Trial Locations

Locations (1)

City of Hope Medical Center; 🇺🇸 Duarte, California, United States