effect of rebamipide on dry eye syndrome related to chronic graft versus host disease a randomized parallel group trial
Not Applicable
- Conditions
- To investigate the treatment efficacy of rebamipide on chronic GVHD dry eye
- Registration Number
- JPRN-UMIN000010433
- Lead Sponsor
- Keio University School of Medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 100
Inclusion Criteria
Not provided
Exclusion Criteria
1 dry eye severity level 4 dews 2007 2 patients having a concern of becoming severe dry eye because of having gvhd in other organs and so on 3 patients with sjogrens syndrome, ocular pemphigoid, and Stevenes-Johnson symdrome 4 patients with a history of ophthalmic surgery 5 patients wearing contact lens 6 patients who will be applied radiation treatment during the study 7 patients dosed cevimeline hydrochloride hydrate and or pilocarpine eye drop or oral drug
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method anterior ocular segment remark corneal sensitivity schrmer test tear film breakup time fluorescein staining lisamine green staining subjective symptom oxidative stress marker in tear film
- Secondary Outcome Measures
Name Time Method