Effectiveness of Egg Versus Whey Protein Powder During Resistance Training

Not Applicable

Completed

• Conditions: Muscle Atrophy
• Interventions: Dietary Supplement: Whole egg powder; Dietary Supplement: Whey protein powder; Dietary Supplement: Maltodextrin placebo

• Registration Number: NCT05206253
• Lead Sponsor: University of Saskatchewan

Brief Summary

Consumption of whole eggs has recently been shown to stimulate muscle protein synthesis to a greater degree than consumption of egg whites after a resistance training session. It is theorized that the egg yoke contains bio-active nutrients that enhance the protein provided by egg whites. The study will evaluate the effect of whole egg powder compared to whey protein powder and placebo over 12 weeks of resistance training in men and women who are participating in resistance training programs.

Detailed Description

Consuming whole eggs after resistance training sessions appears to be more effective for simulating muscle protein synthesis that simply consuming egg whites. The egg yolks might enhance the effect of protein derived from egg whites. The study will compare post-exercise supplementation with about 30 grams of protein derived from whole egg powder versus whey protein powder and placebo (maltodextrin) over a 12-week resistance training program. Resistance-trained men and women (n=120) will be randomized to consume either the whole-egg powder, whey protein powder or maltodextrin after resistance training 6 times per week for 12 weeks. The primary outcome measure is change in lean tissue mass. Secondary measures include change in fat mass, change in arm and leg muscle thickness, change in bench press, squat, and knee extension strength, and change in fasting blood glucose.

Study Timeline

• Study First Submitted: 2022-01-11
• Study First Submitted QC: 2022-01-11
• Study First Posted: 2022-01-25
• Study Start: 2022-05-30
• Primary Completion: 2023-08-31
• Study Completion: 2023-08-31
• Status Verified: 2024-05
• Last Update Submitted: 2024-05-24
• Last Update Posted: 2024-05-29

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 115

Inclusion Criteria

• Resistance training experience for at least one year

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Exclusion Criteria

• Having taken any nutritional supplements the past 30 days
• Currently using anabolic steroids
• Currently taking corticosteroids
• Allergies to dairy or egg products
• Identifying any medical conditions as determined by the "Get Active Questionnaire"

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Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Whole egg powder	Whole egg powder	Dietary supplementation with whole egg powder after resistance training sessions
Whey protein powder	Whey protein powder	Dietary supplementation with whey protein powder after resistance training sessions
Maltodextrin placebo	Maltodextrin placebo	Dietary supplementation with maltodextrin placebo after resistance training sessions

Primary Outcome Measures

Name	Time	Method
Change in lean tissue mass	12 weeks	Lean tissue mass measured by DXA

Secondary Outcome Measures

Name	Time	Method
Change in leg squat strength	12 weeks	Leg squat strength (kg)
Change in triceps muscle thickness	12 weeks	triceps muscle thickness measured by ultrasound
Change in bench press strength	12 weeks	Bench press strength (kg)
Change in fasting glucose	12 weeks	Fasting glucose
Change in biceps muscle thickness	12 weeks	biceps muscle thickness measured by ultrasound
Change in quadriceps muscle thickness	12 weeks	quadriceps muscle thickness measured by ultrasound
Change in hamstrings muscle thickness	12 weeks	hamstrings muscle thickness measured by ultrasound
Change in fat mass	12 weeks	Fat mass measured by DXA
Change in knee extension strength	12 weeks	Isokinetic knee extension torque

Trial Locations

Locations (2)

University of Regina; 🇨🇦 Regina, Saskatchewan, Canada

University of Saskatchewan; 🇨🇦 Saskatoon, Saskatchewan, Canada