Screening and Assessing the Risk Factors and Complications of Chronic Kidney Disease
- Conditions
- Chronic Kidney Disease
- Registration Number
- NCT03246191
- Lead Sponsor
- Chinese PLA General Hospital
- Brief Summary
The study is an observational, cross-sectional study aimed at screening and accessing risk factors and complications for Chinese chronic kidney disease (CKD) patients. To investigate the prevalence of hypertension, cardiovascular and cerebrovascular diseases, protein energy malnutrition（PEM）, cognitive impairment and other complications in the CKD patients. To develop biomarkers of CKD.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 900
- age≥18 years
- clinical diagnosis of CKD
- signed informed consent
- End-stage renal disease(ESRD) or dialysis
- Acute kidney injure(AKI)
- history of solid organ or bone marrow transplantation
- active malignancy within 24 months prior to screening or metastatic cancer
- HIV infection or AIDS
- acute inflammation
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Prevalence of CKD complications baseline hypertension, cardiovascular and cerebrovascular diseases, protein energy malnutrition(PEM), cognitive impairment
Biomarkers of kidney function baseline
- Secondary Outcome Measures
Name Time Method Genetic analyses baseline circulating microRNA
Questionnaire assessing cognitive function baseline Montreal Cognitive Assessment-Basic Chinese Version
Questionnaire assessing depression baseline Beck Depression Inventory scores
Questionnaire assessing risk of malnutrition baseline Malnutrition-Inflammation Score
Questionnaire assessing dietary intake baseline Food Frequency Questionnaire
Questionnaire assessing quality of life baseline Activity of daily living（ADL）and kidney disease quality of life （KDQOLTM-36）