Hypoxia imaging with FMISO PET in brain metastasis
- Conditions
- metastatic brain tumor
- Registration Number
- JPRN-jRCTs011180020
- Lead Sponsor
- Takashi Mori
- Brief Summary
The FMISO accumulation positivity rate of metastatic brain tumors was 39.8%, and the risk ratio of tumor regrowth in the accumulation positive group to the FMISO accumulation negative group was 4.60 (95% CI 1.23-17.2), p = 0.0235, indicating a significantly higher risk of regrowth.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 25
1)metastatic brain tumor whose maximum diameter is equal to or above 5mm in MRI.
2)no treatment history with radiotherapy or surgery to metastatic brain tumor.
3)no meningitis carcinomatosa and dissemination in MRI.
4)KPS equal to or above 70%.
5)Pathologically (histologically or cytologically) proven diagnosis from extra cranial lesion.
6)Patients must sign a study-specific informed consent prior to study entry.
1)patient who can rest in dorsal position for about one hour
2)patient with severe claustrophobia
3)nonage
4)expectant and nursing mothers
5)patient judged unsuitable as a trial subject by the principal investigator
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method FMISO accumulation
- Secondary Outcome Measures
Name Time Method local control survival, overall survival