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临床试验/NCT07003893
NCT07003893已完成不适用

Efficacy of Diaphragmatic Proprioceptive Neuromuscular Facilitation on Functional Capacity and Pulmonary Function in Heavy Twenties Smokers

Al-Zaytoonah University of Jordan1 个研究点 分布在 1 个国家目标入组 40 人开始时间: 2025年7月5日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
已完成
入组人数
40
试验地点
1
主要终点
FEV1/FVC ( % )

研究概览

简要总结

Although research on the health risks of e-cigarettes is still limited, there is increasing evidence of debilitating lung disease and general immune dysfunction from e-cigarettes, leading to various infections. Moreover, there are concerns that e-cigarettes can cause general impairment in life functions and more importantly lung function .Although exercise can help quit smoking and reduce relapses .However, exercise has many other fitness benefits when done regularly for the general population, as well as for smokers. Exercise has been shown to help with smoking cessation, which has been an important factor preventing many smokers, especially younger people, from quitting. Breathing exercises, especially diaphragm exercises improves lung function, lifestyle and health risk factors and thus the risk of developing many chronic diseases. Both aerobic interventions and exercise can reduce the incidence of many of the prevalent cancers initiated by smoking, such as lung cancer. This is important because lung cancer is the most common type of cancer worldwide, and cigarette smoking is responsible for up to 90% of lung cancer cases worldwide.

详细描述

According to predictions by the World Health Organization, the number of smokers who will die from cigarette related diseases will surpass the number of people dying from AIDS, traffic accidents, suicide, and murder combined by 2020. Due to the presence of various harmful substances in cigarettes, smoking can cause many diseases. Nicotine which is one of the major constituents of cigarettes causes arteriosclerosis, coronary artery disease, chronic obstructive pulmonary disease (COPD), and other problems that result not only in low cardiopulmonary function but also in relatively diminished daily living ability and endurance in smokers compared with that in non-smokers. Moreover, it is common knowledge that smoking is very highly correlated with occurrence of respiratory diseases. Diaphragmatic breathing is a good technique for respiration and relaxation of the lungs because it enables sufficient exchange of oxygen and carbon dioxide. Diaphragmatic breathing is reported to be effective in improvement of ventilation efficiency, dyspnea, and activity ability; reduction of metabolic acidosis; alleviation of back pain; spine correction; abdominal strengthening; and improvement of body composition and flexibility. In our current social climate, the number of male smokers in their twenties is rapidly increasing and this trend is becoming a social problem. Our study attempts to verify the effects of diaphragmatic proprioceptive neuromuscular facilitation on functional capacity and pulmonary functions in in heavy twenties smokers.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Treatment
盲法
Single (Participant)

入排标准

年龄范围
20 Years 至 29 Years(Adult)
性别
Male
接受健康志愿者
否

入选标准

  • •Adults aged 20-29 years.
  • •Subjects who have been smoking for 1 to 3 years.
  • •Subjects who not receiving medical treatment for respiratory diseases.
  • •Subjects who have clean family medical history.

排除标准

  • •Subjects who smoke cigars other than filtered cigarettes or tobacco pipes.
  • •Subjects with respiratory proplems.
  • •Participation in another clinical trial within the last 30 days.
  • •Endocrine and metabolic disorders (eg, hypothyroidism, hypercalcemia, diabetes mellitus, diabetes insipidus).
  • •Neurologic and psychiatric disorders (who can not understand the research project ).

研究组 & 干预措施

Control group

Active Comparator

perform exercises using aerobic exercises only

干预措施: Diaphragmatic Proprioceptive Neuromuscular Facilitation + Aerobic exercises (Other)

Experimental group

Experimental

perform diaphragmatic proprioceptive neuromuscular facilitation and aerobic exercise

干预措施: Diaphragmatic Proprioceptive Neuromuscular Facilitation + Aerobic exercises (Other)

结局指标

主要结局

FEV1/FVC ( % )

时间窗: pre and post 4 weeks

The ratio of the forced expiratory volume in the first one second to the forced vital capacity of the lungs. That can reflect pulmonary function , using portable spirometer ( SP 80B,China)

FEV1 ( liters )

时间窗: Pre and post 4 weeks

Forced expiratory volume in 1 second that can reflect pulmonary function , using portable spirometer ( SP 80B,China)

PEF ( liters / minute )

时间窗: pre and post 4 weeks

Peak expiratory flow (PEF), a key indicator of lung function,using portable spirometer ( SP 80B,China)

FVC ( liters )

时间窗: Pre and post 4 weeks

Forced vital capacity (FVC) is the total amount of air exhaled during the FEV test. Forced expiratory volume and forced vital capacity are lung function tests , using portable spirometer ( SP 80B , China )

Chest expansion ( centimeter )

时间窗: Pre and post 4 weeks

A simple, noninvasive pulmonary function test used to assess chest wall mobility and, to a lesser extent, lung function , using tape measurement.

次要结局

  • Functional capacity(Pre and post 4 weeks)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Mohamed Saied Zidan

Assistant prof dr

Al-Zaytoonah University of Jordan

研究点 (1)

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