Postoperative Epidural Analgesia in Spine Fusion Surgery
Overview
- Phase
- Phase 2
- Intervention
- 0.125% Bupivacaine HCL @ 4-5 ml/h
- Conditions
- Pain
- Sponsor
- Assiut University
- Enrollment
- 60
- Locations
- 1
- Primary Endpoint
- Assessment of pain
- Status
- Completed
- Last Updated
- 13 years ago
Overview
Brief Summary
we aim to compare the analgesic effect of 0.125% bupivacaine HCL, 0.125% bupivacaine HCL + Morphine sulphate 3 mg, 0.125% bupivacaine HCL + Fentanyl 100 micro gram both at rest and mobilization maneuvers.
Investigators
Omnia Askar
assistant lecturer of anesthesia and ICU, Assiut University
Assiut University
Eligibility Criteria
Inclusion Criteria
- •patients undergoing spine fusion surgery.
Exclusion Criteria
- •Drug addiction. Intraoperative dural tear. Uses of opioids drug for any reason in the previous 48 hours. Mental dysfunction. Spinal fusion for any infectious or malignant causes.
Arms & Interventions
Bupivacaine
0.125% Bupivacaine HCL @ 4-5 ml/h
Intervention: 0.125% Bupivacaine HCL @ 4-5 ml/h
Bupivacaine, Morphine
0.125% Bupivacaine HCL , Morphine sulphate 3 mg @ 3-5 ml/h
Intervention: 0.125% Bupivacaine HCL , Morphine sulphate @ 3 mg 3-5 ml/h
Bupivacaine, Fentanyl
0.125% Bupivacaine, Fentanyl 100 mic @ 3-5 ml/h
Intervention: 0.125% Bupivacaine, Fentanyl 100 mic @ 3-5 ml/h
Outcomes
Primary Outcomes
Assessment of pain
Time Frame: first 3 postoperative days
• Pain will be assessed using the VAS ranging from "0" (no pain) to "10" (worst imaginable pain). Pain will be evaluated at rest, while coughing, and during mobilization. Maneuvers of particular clinical importance for postoperative mobilization (alone and with help) will be chosen: Turning in bed, standing in front of the bed and walking, and using the toilet without help. The time needed until the patient can first successfully perform these maneuvers will be documented.
Secondary Outcomes
- assessment of patients' satisfaction(First 3 postoperative days)