Evaluation of the Effectiveness of a Protein Pulse-Feeding Pattern in Elderly Patients
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 68
- 试验地点
- 1
- 主要终点
- Lean mass (dual energy X-ray absorptiometry [DEXA] and bioelectrical-impedance analysis [BIA])
研究概览
简要总结
The researchers tested the hypothesis that a protein pulse-feeding pattern was more efficient in improving muscle mass and immune functions than was a protein spread-feeding pattern, after 45 days, in elderly malnourished patients.
详细描述
To estimate the amelioration of the accretion in protein and the immunizing deficit thanks to a nutrition "PULSEE" ( to hold on 80 % of the proteic by day in on meal) with a proteic distributed all along the day for old subjects having a denutrition
To also estimate that the diminution of the morbidity decrease (infections, bedsores) the average during the stay and the mortality according to 2 modalities of grip nutritional
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 70 Years 至 —（Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Must be malnourished
- •Hospitalization into a geriatric rehabilitation care unit
- •Age > 70 years
- •C-reactive protein (CRP) < 50 mg/l
排除标准
- •Enteral or parenteral nutrition
- •Renal, cardiac or digestive insufficiency
- •Pacemaker
- •Mini-Mental State (MMS) < 15
研究组 & 干预措施
1
Protein pulse-feeding
干预措施: Protein pulse-feeding (Dietary Supplement)
2
Spread diet
干预措施: Spread diet (Dietary Supplement)
结局指标
主要结局
Lean mass (dual energy X-ray absorptiometry [DEXA] and bioelectrical-impedance analysis [BIA])
时间窗: 42 days
次要结局
- Immune functions(42 days)
- Hand-grip strength(42 days)
- Biological nutritional parameters(42 days)
- Mortality and morbidity (infections and bedsores)(42 days)
- Activity of Daily Living (ADL)(42 days)
- Plasmatic amino acid levels(42 days)