ACLF in Zagazig University Hospitals
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 300
- 试验地点
- 1
- 主要终点
- improvement of the patients score according to SOFA score (AASLD and EASL guidelines)
研究概览
简要总结
Rationale:
To identify the prevalence of Acute-on-chronic liver failure in Zagazig University Hospitals.
The question of the research:
How much the prevalence of Acute-on-chronic Liver Failure in Zagazig University Hospitals?
The aim of the work:
The aim of the study is to identify the presence of Acute-on-chronic Liver Failure in Zagazig University Hospitals
Objectives:
To estimate the prevalence of Acute-on-chronic Liver Failure in Zagazig University Hospitals.
Subjects and Methods:
I . Technical Design:
- Site of the study: Gastroenterology and Hepatology Unit- Zagazig University Hospitals
- Sample size: ''all patients admitted to Gastroenterology and Hepatology Unit with the criteria of ACLF according to EASL-AASLD from June 2017 to December 2017 were included in this study''.
II . OPERATIONAL DESIGN:
- Type of the study: a prospective study.
- Full medical history - taking.
- Full clinical examination.
- Laboratory investigations including Routine laboratory investigation " CBC, Liver functions test, kidney functions test and prothrombin time "
III. Administrative Design:
- Approvals obtained for performing the study from the official or governmental department.
- An ethical committee from the faculty of medicine and patients included in the study.
Results:
Collected data will be presented in tables and suitable graphs and analyzed according to standard statistical methods
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •all patients admitted to Gastroenterology and Hepatology Unit with the criteria of ACLF according to EASL-AASLD will be included in this study.
排除标准
- •no any exclusion criteria
结局指标
主要结局
improvement of the patients score according to SOFA score (AASLD and EASL guidelines)
时间窗: 24 weeks from first recruiting
follow up of participants until the patients recover
次要结局
- death of the patient(24 weeks from first recruiting)
研究者
salem youssef mohamed
assistant professor of internal medicine, gastroenterology and hepatology unit
Zagazig University