JPRN-UMIN000035263CompletedPhase 4
Study for the effect of SGLT2 inhibitors in high risk patients of dialysis with type 2 diabetes - The effect of SGLT2 inhibitors in patients with renal dysfunction
Kurihara Naika Clinic0 sites75 target enrollmentStarted: December 15, 2018Last updated:
Conditions
Trial Snapshot
- Phase
- Phase 4
- Status
- Completed
- Sponsor
- Enrollment
- 75
Study Overview
Brief Summary
%DeGFR+2y in patients who were treated with SGLT2i was significantly increased compared with the patients not treated with SGLT2i (2.3 and -21.7%, respectively; P < 0.0001). There was no increase in serious adverse events including acute kidney injury. SGLT2i was safe, and prevented further eGFR decline in patients with type 2 diabetes and advanced renal dysfunction.
Study Design
- Study Type
- Observational
Eligibility Criteria
- Ages
- ot applicable to ot applicable (—)
- Sex
- All
Inclusion Criteria
- Not provided
Exclusion Criteria
- •1)type 1 diabetes 2)severe liver dysfunction 3)pregnancy, nursing woman or possibly pregnant woman 4)severe diabetic ketosis, diabetic coma 5)severe infection, pre and post operation , severe trauma 7) uncontrolled diet therapy 8) poor adherence for medication 9) patients who thought to be inappropriate to enter this study for some reasons by physician's judgments
Investigators
Similar Trials
Completed
Phase 4
Metabolic Responses of Dapagliflozin vs Sitagliptin in T2DM Patients Inadequately Controlled With Insulin TherapyKetonemiaType 2 DiabetesNCT03959501The University of Hong Kong60
Unknown
Phase 4
Effects of SGLT2 Inhibitor in Diabetic Patients With Coronary Artery DiseaseCoronary Disease With Diabetes MellitusNCT03398577Sheba Medical Center61
Completed
Not Applicable
A retrospective study: Effects of additional SGLT2-inhibitor therapy on renal functions in patients with type 2 diabetes mellitus and stage 3b and 4 chronic kidney diseasetype 2 diabetes mellitusJPRN-UMIN000035278Jinnouchi Hospital Diabetes Care Center42
Completed
Not Applicable
Effects of treatment with SGLT2 inhibitor on the initiation of continuous positive airway pressure therapy in type 2 diabetic patients with obstructive sleep apnea syndromeType 2 diabetesJPRN-UMIN000045226Akishima Clinic16
Not yet recruiting
Not Applicable
SGLT2 Inhibitors and Perioperative PeriodPerioperative ComplicationNCT06326528Assiut University100