Augmented renal clearance (ARC) and Meropenem concentratio
Phase 2
Recruiting
- Conditions
- Augmented renal clearance (ARC).
- Registration Number
- IRCT20120703010178N19
- Lead Sponsor
- Shahid Beheshti University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 20
Inclusion Criteria
serum creatinin 0.7mg/dl and lower
Sequential Organ Failure Assessment (SOFA) score 4 and lower
Augmented renal clearance (ARC ) scoring 7 and higher
Augmented renal clearance in trauma intensive Care (ARCTIC) scoring 7 and higher
12 hour - Clearance creatinin 130 ml/min and higher
Exclusion Criteria
Pregnancy and Lactation
Age lower than 18 yr
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Serum concentration of Meropenem. Timepoint: 1 hour after end of infusion, 30 minute before next dose. Method of measurement: HPLC.;Serum creatinin. Timepoint: Daily from the beginning of the study to the 14th day of the study. Method of measurement: Laboratory apparatus, Calorimetric method.;Urine volume. Timepoint: 0,3,7,10,14 day of enter to study. Method of measurement: Urine bag.
- Secondary Outcome Measures
Name Time Method