Methods for Nutritional Assessment in Cirrhosis

• Conditions: Malnutrition; Liver Cirrhosis; Cachexia

• Registration Number: NCT02926261
• Lead Sponsor: Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran

Brief Summary

Nutritional status in patients with cirrhosis has been shown to have a direct influence on the prognosis of these patients, it is related to higher mortality and it has been linked to the developement and perpetuation of certain complications such as hepatic encephalopathy, ascites and spontaneous bacterial peritonitis.

Despite the importance of nutritional status in this patients, most of the methods for its assessment are still not completely reliable or not easily accessible; therefore, evaluating nutritional status in the daily clinical practice is still a complex task.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2016-10-05
• Study First Submitted QC: 2016-10-05
• Study First Posted: 2016-10-06
• Study Start: 2016-12
• Status Verified: 2020-01
• Last Update Submitted: 2020-02-27
• Last Update Posted: 2020-02-28
• Primary Completion: 2020-12
• Study Completion: 2021-12

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 180

Inclusion Criteria

• Diagnosis of cirrhosis
• No restriction of etiology
• 18-75 years
• Child-Pugh stage A/B/C
• Signed informed consent

Exclusion Criteria

• Pregnancy
• Extremity amputation
• Malignancy different from hepatocellular carcinoma

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Nutritional status	Evaluation at time of recruitment	Characterization of nutritional status by three methods of nutritional assessment; * Bioelectrical impedance vector analysis; * CT scan; * Handgrip strength

Trial Locations

Locations (1)

Instituto Nacional de Ciencias Médicas y Nutrición "Salvador Zubirán"; 🇲🇽 Mexico City, DF, Mexico