Postmastectomy Pai

Not Applicable

• Conditions: Cancer; Surgery; post-mastectomy, pain , pregabalin, cancer

• Registration Number: PACTR201705002266194
• Lead Sponsor: ational Cancer Institute

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2017-05-05
• Last Update Posted: 2023-05-29

Recruitment & Eligibility

• Status: Other
• Sex: Female
• Target Recruitment: 210

Inclusion Criteria

Patients scheduled for elective breast surgery {either modified radical mastectomy(MRM) or conservative breast surgery (CBS)}combined with axillary dissection. ASA physical status I-II-III

Exclusion Criteria

-History of pregabalin or gabapentin allergy.
-History of allergy to NSAIDs, morphine and paracetamol.
-Pregnancy and lactation.
-BMI > 40 kg/m^2.
-Patients with major liver, renal, cardiorespiratory,endocrinal or haematological disorder.
-Patients with preexisting pain which necessitates morphine at daily dose of 30 mg or more (or equivalent opioids).
History of pregabalin intake in the preceding 3 months.
-History of drug abuse.
-Expected another breast surgery in the subsequent period.
-Neuropsychiatric disorder.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Pain by using VAS

Secondary Outcome Measures

Name	Time	Method
Post-mastectomy neuropathic pain using DN4;Side effects of pregabalin