Prediction of preeclampsia/eclampsia in pregnant wome

Not Applicable

Completed

• Conditions: Topic: Reproductive Health & Childbirth; Subtopic: Reproductive Health & Childbirth; Disease: Reproductive Health & Childbirth; Pregnancy and Childbirth; Preeclampsia

• Registration Number: ISRCTN87470468
• Lead Sponsor: Oxford University Hospitals NHS Trust

Brief Summary

2019 Results article in https://www.ncbi.nlm.nih.gov/pubmed/31401877 results (added 14/08/2019) 2021 Results article in https://pubmed.ncbi.nlm.nih.gov/33207235/ (added 22/03/2021) 2021 Results article in https://pubmed.ncbi.nlm.nih.gov/34785177/ secondary analysis (added 28/04/2022)

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2015-11-20
• Study Completion: 2016-07-08
• Last Update Posted: 9 May 2022

Recruitment & Eligibility

• Status: Completed
• Sex: Female
• Target Recruitment: 370

Inclusion Criteria

1. Female aged between 18-45 years
2. Pregnant >24 weeks
3. Able to consent
4. Singleton pregnancy
5. New onset hypertension (Stratified as below – Management) AND/OR
6. New onset proteinuria AND/OR
7. New onset oedema/headache/visual Disturbance AND/OR
8. New onset hepatic/liver tenderness AND/OR epigastric pain AND/OR
9. Any other clinical suspicion of PE

Exclusion Criteria

1. Unable to consent
2. Age less than 18 or over 45 at the time of recruitment
3. Unable to speak English well enough to understand the study information
4. Unwilling to participate
5. Preexisting preeclampsia
6. Multiple pregnancy or higher order pregnancy
7. Any significant disease or disorder which in the opinion of the investigator may either put the participants at risk or may influence the result of the study or the participant’s ability to participate in the study

Study & Design

• Study Type: Interventional
• Study Design: Not specified