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Clinical Trials/NCT04442321
NCT04442321
Completed
Not Applicable

Effectiveness of Ultrasound-Guided Percutaneous Electrical Stimulation on Radial Nerve With Exercises in Patients With Lateral Epicondylalgia

Universidad Complutense de Madrid1 site in 1 country60 target enrollmentSeptember 1, 2020
ConditionsTennis Elbow

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Tennis Elbow
Sponsor
Universidad Complutense de Madrid
Enrollment
60
Locations
1
Primary Endpoint
Changes in Elbow Pain Intensity between baseline and follow-up periods
Status
Completed
Last Updated
7 months ago

Overview

Brief Summary

Lateral epicondylalgia is a common musculoskeletal condition that approximately affects 1-3% of the general population. Several authors have found greater mechanical pain sensitivity in the radial nerve when compared with healthy subjects. Radial tunnel syndrome exhibits a similar clinical presentation to lateral epicondylalgia. Percutaneous electrical stimulation has shown reduce pain in several conditions. Percutaneous electrical stimulation on the radial nerve could cause an important relief in lateral epicondylalgia.

Hypothesis: Percutaneous electrical stimulation on radial nerve plus exercise therapy in patients with lateral epicondylalgia is better than sham percutaneous electrical stimulation plus exercise.

Detailed Description

Randomized, double-blind, placebo controlled clinical trial, using Percutaneous Electrical Nerve Stimulation (PENS). PENS is technique to provide a transcutaneous electrical nerve stimulation current throughout needling filaments place close to the nerve. Study Aims: Aim #1: The primary aim of the study is to compare the effect of the short, mid and long-term of PENS on intensity of pain as measured by numeric pain rating scale and disability as measured by Patient Rated Tennis Elbow Evaluation (PRTEE) in patients with lateral epicondylalgia with random assignment to two treatments: PENS plus exercise program or Sham PENS plus exercise program. Aim #2: The secondary aim of the study is to compare the effect of the short, medium and long-term of PENS on disability as measured by DASH questionnaire, and psychological factors (fear and avoidance and catastrophism) and Global Rating of Change (GRoC) in patients with lateral epicondylalgia with random assignment to two treatments: PENS plus exercise program or Sham PENS plus exercise program.

Registry
clinicaltrials.gov
Start Date
September 1, 2020
End Date
December 30, 2024
Last Updated
7 months ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Lateral epicondylalgia symptoms confirmed with at least 2 of the 4 following test:
  • pain during palpation of lateral epicondyle
  • pain on resisted wrist extension
  • pain on resisted middle finger extension
  • pain during hand-grip.

Exclusion Criteria

  • History of fractures, luxations, surgery and/or musculoskeletal disorders in upper limb.
  • Neurological disorders, inflammatory and/or degenerative diseases.
  • Having received as treatment techniques that involve needles on the previous 6 months to study enrollment, or having received percutaneous electrical stimulation as a treatment before.
  • Cervical pathology, fibromyalgia, unstable cardiovascular diseases, pregnant women or under suspect of pregnancy.
  • Contraindications of needle's insertions: anticoagulant therapy, needle phobia, diabetes, hypothyroidism, lymphoedema, muscular diseases).
  • Contraindications of electrical current application.

Outcomes

Primary Outcomes

Changes in Elbow Pain Intensity between baseline and follow-up periods

Time Frame: Baseline, 1 week post-intervention, and 1, 3, 6 and 12 months after the intervention

Pain intensity measured with a 10 (0 - No pain - 10 The worst pain) numeric rating scale

Secondary Outcomes

  • Changes in Elbow Related-Disability between baseline and follow-up periods(Baseline,1 week post-intervention, and 1, 3, 6 and 12 months after the intervention)
  • Changes in Upper Extremity Related-Disability between baseline and follow-up period(Baseline, 1 week post-intervention, and 1, 3, 6 and 12 months after the intervention)
  • Changes in Kinesiophobia between baseline and follow-up periods(Baseline,1 week post-intervention, and 1, 3, 6 and 12 months after the intervention)
  • Changes in Self-perceived Improvement between baseline and follow-up periods(Baseline,1 week post-intervention, and 1, 3, 6 and 12 months after the intervention)
  • Changes in Pain Catastrophizing between baseline and follow-up periods(Baseline, 1 week post-intervention, and 1, 3, 6 and 12 months after the intervention)

Study Sites (1)

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