Personalized Exercise Oncology (PEXO) - Study

University Hospital Heidelberg1 site in 1 country800 target enrollmentNovember 26, 2018

ConditionsCancer Health Behavior

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: Cancer
Sponsor: University Hospital Heidelberg
Enrollment: 800
Locations: 1
Primary Endpoint: Patient Clusters
Status: Active, not recruiting
Last Updated: last year

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

The Goal of the study is to identify trait-homogenous groups of cancer patients in regards to their physical activity associated health literacy. Based on these Groups, individualized exercise protocols and educative strategies can be developed which may increase the efficacy of the exercise therapy and increases the likelihood that patient get involved in physical activity.

Registry

clinicaltrials.gov

Start Date

November 26, 2018

End Date

February 2026

Last Updated

last year

Study Type

Observational

Sex

All

Investigators

Sponsor

University Hospital Heidelberg

Responsible Party

Principal Investigator

Joachim Wiskemann

Head of Exercise Onoclogy, Principal Investigator, Associated Professor

University Hospital Heidelberg

Eligibility Criteria

Inclusion Criteria

•Histologically confirmed cancer diagnosis
•Females and males ≥18 years of age
•Undergoing either chemo-, immune-, radio- or anti-hormonal treatment
•Last surgery more than 6 weeks in the past
•Ability to understand English or German
•Be able to provide and understand informed consent
•Have an Eastern Cooperative Oncology Group (ECOG) Performance Score of ≤ 2

Exclusion Criteria

•Heart insufficiency \> NYHA III (New York Heart Association) or uncertain arrhythmia
•Uncontrolled hypertension
•Severe renal dysfunction (GFR \< 30%, Creatinine\> 3mg/dl)
•Reduced standing or walking
•Current pregnancy
•Any other evidence in the medical record of an absolute contraindication for exercise

Outcomes

Primary Outcomes

Patient Clusters

Time Frame: through study completion, an average of 1 year

Identification of different, trait-homogenous patient clusters

Secondary Outcomes

Questionnaire: Health Literacy(through study completion, an average of 1 year)
Questionnaire: Physical Activity Associated Health Literacy(through study completion, an average of 1 year)
Questionnaire: Health Related Quality of Life(through study completion, an average of 1 year)
Questionnaire: Fatigue(through study completion, an average of 1 year)
Questionnaire: Physical Activity(through study completion, an average of 1 year)
Questionnaire: Brief Pain Inventory (BPI)(through study completion, an average of 1 year)
Questionnaire: Emotion Thermometers(through study completion, an average of 1 year)