Efficacy of autologous platelet rich plasma(PRP) versus growth factor concentrate(GFC) in moderate androgenetic alopecia: a randomized open-label trial
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 70
- 试验地点
- 1
- 主要终点
- Primary outcomes Global photographic assessment of improvement at the vertex and frontal view. Graded 1 to 7 as dense, moderate, minimal regrowth and dense, moderate, minimal, no loss. First three grades were considered as responders and latter four as non responders.
研究概览
简要总结
Androgenetic alopecia (AGA) is the most often encountered chronic non-scarring form of hair loss. It affects both men and women. It is androgen dependent and characterised by progressive thinning of hair, reduced density, and recession of hair line. Hair is considered an important component of self-image. Hair loss affects the self-esteem of an individual and can lead to impaired quality of life. There are various treatment options available for AGA. Platelet rich plasma (PRP) is a centrifuged analogous concentration of platelets which have growth factors which have significant effect on hair growth. Growth factor concentrate (GFC) therapy is modified PRP technique which have gained attention in the treatment of AGA in recent times. To our knowledge there is a paucity of studies comparing the outcomes of PRP and GFC for treatment of AGA. Hence, we aim to compare the efficacy of both in Indian patients.
研究设计
- 研究类型
- Interventional
- 分配方式
- Other
- 盲法
- None
入排标准
- 年龄范围
- 18.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •Patients with androgenetic alopecia (Hamilton-Norwood grade 2-4; Ludwigs scale grade 1 and 2).
排除标准
- •Patients age less than 18 years.
- •Patients with infective and inflammatory scalp dermatoses.
- •Patients with blood diathesis.
- •Patients on treatment for AGA in last 3 months.
结局指标
主要结局
Primary outcomes Global photographic assessment of improvement at the vertex and frontal view. Graded 1 to 7 as dense, moderate, minimal regrowth and dense, moderate, minimal, no loss. First three grades were considered as responders and latter four as non responders.
时间窗: Primary outcomes Global photographic assessment of improvement at the vertex and frontal view. Graded 1 to 7 as dense, moderate, minimal regrowth and dense, moderate, minimal, no loss. First three grades were considered as responders and latter four as non responders. | From baseline to 16 weeks terminal hair count, total hair density, proportion of anagen hairs will be assessed and documented.
From baseline to 16 weeks terminal hair count, total hair density, proportion of anagen hairs will be assessed and documented.
时间窗: Primary outcomes Global photographic assessment of improvement at the vertex and frontal view. Graded 1 to 7 as dense, moderate, minimal regrowth and dense, moderate, minimal, no loss. First three grades were considered as responders and latter four as non responders. | From baseline to 16 weeks terminal hair count, total hair density, proportion of anagen hairs will be assessed and documented.
次要结局
- Secondary outcomes as subject satisfaction with hair fall, hair density & texture on a scale of 1-10 .
研究者
Dr Yogindher singh
Sri Venkateshwaraa medical college hospital