COMPARITIVE EFFICACY OF HUMIDIFIED OXYGEN THERAPY VERSUS HUMIIDIFIED OXYGEN THERAPY ALONG WITH NEBULISED 3% HYPERTONIC SALINE IN CHILDREN WITH ACUTE BRONCHIOLITIS-A RANDOMISED CONTROL TRIAL
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- Clinical severity score and duration of oxygen therapy will be used to assess improvement and outcome of the study. Clinical severity score ranging from 1 to 3 are taken as mild, score 4 to 8 as moderate and score more than 8 as severe respiratory distress. Total duration of oxygen therapy will be calculated. Lower the duration of oxygen therapy implies better the treatment modality
研究概览
简要总结
THIS IS A RANDOMISED CONTROL TRIAL COMPARING EFFICACY OF HUMIDIFIES OXYGEN THERAPY VERSUS HUMIDIFIED OXYGEN THERAPY ALONG WITH NEBULISED 3 PERCENTAGE HYPERTONIC SALINE IN CHILDREN WITH ACUTE BRONCHIOLITIS. THE PRESENT STUDY HYPOTHESIZED THAT SIMPLY INHALATION OF HYPERTONIC SALINE SOLUTION WITH HUMIDIFIED OXYGEN THERAPY IN BABIES WITH BRONCHIOLITIS MAY IMPROVE THERE CLINICAL SEVERITY SCORES THEREBY SHORTENING THE LENGTH OF HOSPITALISATION. 3 PERCENTAGE HYPERTONIC SALINE WILL REDUCE AIRWAY EDEMA AND IMPROVE MUCOCILIARY FUNCTION BY ITS ABILITY TO LOWER THE VISCOSITY OF SECRETIONS.
研究设计
- 研究类型
- Interventional
- 分配方式
- Coin toss, Lottery, toss of dice, shuffling cards etc
- 盲法
- None
入排标准
- 年龄范围
- 2.00 Month(s) 至 2.00 Year(s)（—）
- 性别
- All
入选标准
- •All children of age group 2months to 2years with moderate bronchiolitis with SpO2 less than 92percentage correctable with oxygen whose parents gave informed consent.
排除标准
- •1.Children previously diagnosed with chronic respiratory disease, cardiac disease and immunodeficiency 2.Children with previous wheezing episode.
- •3.Premature babies less than 34 weeks of gestation.
- •4.Mild and severe bronchiolitis.
结局指标
主要结局
Clinical severity score and duration of oxygen therapy will be used to assess improvement and outcome of the study. Clinical severity score ranging from 1 to 3 are taken as mild, score 4 to 8 as moderate and score more than 8 as severe respiratory distress. Total duration of oxygen therapy will be calculated. Lower the duration of oxygen therapy implies better the treatment modality
时间窗: 4 weeks
次要结局
- data recorded in the prestructured proforma & daily assessment chart will be collected & analysed using SPSS software(4 weeks)
研究者
DR SHERIN J K
MALANKARA ORTHODOX SYRIAN CHURCH MEDICAL COLLEGE