CTRI/2017/11/010428
Recruiting
未知
Intensity modulated radiotherapy with IGRT for Post cricoid and upper esophageal cancer: Prospective observational study
Varian Medical Systems Inc0 sites0 target enrollmentTBD
Overview
- Phase
- 未知
- Intervention
- Not specified
- Conditions
- Health Condition 1: null- Biopsy proven Squamous Cell Carcinoma of Post- cricoid and Upper cervical esophagus
- Sponsor
- Varian Medical Systems Inc
- Status
- Recruiting
- Last Updated
- 4 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •1\.Biopsy\-proven squamous cell carcinoma of the post cricoid and upper esophagus, with AJCC 7th edition stage T1\-3N0\-1,2M0
- •2\.Lesions of the cervical and upper thoracic esophagus but not involving the mid and lower third of thoracic esophagus
- •3\.Suitable for radical treatment with RT alone or Concurrent Chemo\-radiotherapy
- •4\.No significant co\-morbidities that would interfere with treatment
- •5\.Reliable for follow\-up and signed informed consent.
- •6\.Karnofsky performance status (KPS) between 70 and 100
Exclusion Criteria
- •1\.Age less than 18;
- •2\.Previous treatment (e.g. chemotherapy, radiation therapy, laser therapy or surgery) for esophageal or head and neck cancer (gastrostomy or PEG does not constitute exclusion criteria);
- •3\.Previous thoracic radiation therapy for any cause;
- •4\.Evidence of other uncontrolled malignancies;
- •5\.Severe compromised pulmonary function due to pulmonary disease eg. COPD
- •6\.Scoliosis/kyphosis;
- •7\.Failure to complete all baseline assessments required for the study.
- •8\.Dysfunctional larynx (gross exolaryngeal extension, need for tracheostomy)
Outcomes
Primary Outcomes
Not specified
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