Intensity modulated radiotherapy with IGRT for Post cricoid and upper esophageal cancer: Prospective observational study

Not Applicable

• Conditions: Health Condition 1: null- Biopsy proven Squamous Cell Carcinoma of Post- cricoid and Upper cervical esophagus

• Registration Number: CTRI/2017/11/010428
• Lead Sponsor: Varian Medical Systems Inc

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 24 November 2021

Recruitment & Eligibility

• Status: Open to Recruitment
• Sex: Not specified
• Target Recruitment: 0

Inclusion Criteria

1.Biopsy-proven squamous cell carcinoma of the post cricoid and upper esophagus, with AJCC 7th edition stage T1-3N0-1,2M0

2.Lesions of the cervical and upper thoracic esophagus but not involving the mid and lower third of thoracic esophagus

3.Suitable for radical treatment with RT alone or Concurrent Chemo-radiotherapy

4.No significant co-morbidities that would interfere with treatment

5.Reliable for follow-up and signed informed consent.

6.Karnofsky performance status (KPS) between 70 and 100

Exclusion Criteria

1.Age less than 18;

2.Previous treatment (e.g. chemotherapy, radiation therapy, laser therapy or surgery) for esophageal or head and neck cancer (gastrostomy or PEG does not constitute exclusion criteria);

3.Previous thoracic radiation therapy for any cause;

4.Evidence of other uncontrolled malignancies;

5.Severe compromised pulmonary function due to pulmonary disease eg. COPD

6.Scoliosis/kyphosis;

7.Failure to complete all baseline assessments required for the study.

8.Dysfunctional larynx (gross exolaryngeal extension, need for tracheostomy)

Study & Design

• Study Type: Observational
• Study Design: Not specified