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A clinical study to evaluate the effect of two herbal drugs, bhunimba kshara and katuki churna in combination with restricted diet, exercise and yoga in patients of Non- alcoholic fatty liver disease.

Phase 2
Conditions
Health Condition 1: K760- Fatty (change of) liver, not elsewhere classified
Registration Number
CTRI/2019/03/018039
Lead Sponsor
All India Institute of Ayurveda
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Open to Recruitment
Sex
Not specified
Target Recruitment
0
Inclusion Criteria

Non-alcoholic fatty liver disease patient who diagnosed by abdomen ultrasonic examination and Non-drinker Or total abstainer or with alcohol intake of less than 20g per day for female and less than 30 g per day for males

NAFLD confirmed by USG with or without having symptoms like fatigue, mild discomfort in the upper quadrant of abdomen

3. Voluntary agreement and enrolment.

Exclusion Criteria

The ratio of AST and ALT over 2

Metabolic syndromes such as Type I and II diabetes mellitus hypertension

Thyroid dysfunctions hypothyroidism or hyperthyroidism

Any dysfunction of liver besides non-alcoholic fatty liver disease like viral hepatitis liver parenchymal disease, ascites, portal hypertension, Hepato-cellular carcinoma, Auto- immune hepatitis, Primary biliary cirrhosis, Wilsons disease, and liver transplantation or any other conditions interfering with the result of the treatment Alcoholic fatty liver disease patient

Prior treatment with any medicine which affects the treatment of non-alcoholic fatty liver disease within 3 months

Patient taking any product which affects the BMI or hyperlipidemia

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Changes in the infiltration of fat globules in Ultrasonography (USG) findings along with changes in clinical presentationsTimepoint: Zero <br/ ><br>Thirteith day
Secondary Outcome Measures
NameTimeMethod
iver function tests <br/ ><br>Lipid profile <br/ ><br>Changes in body weight, BMI and waist hip ratio <br/ ><br>Relief of the following symptoms like Fatigue, Pain in epigastrium, Anorexia, Nausea <br/ ><br>Overall improvement in quality of lifeTimepoint: Zero <br/ ><br>Thirty
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