Assessment of the work of breathing of children receiving nasal high flow oxyge

Not Applicable

Recruiting

• Conditions: Respiratory distress; Respiratory - Other respiratory disorders / diseases

• Registration Number: ACTRN12610000549022
• Lead Sponsor: Dr Jan Kelly

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2010-07-08
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

Respiratory distress (either primary or secondary) who
are receiving nasal high flow oxygen or continuous positive airways pressure; or require greater than or equal to 2L/min of oxygen via nasal prongs, and have at least moderate work of breathing as determined by the treating team

Exclusion Criteria

Children who require intubation and invasive ventilation.
Children with a contraindication to nasal canulae and non invasive ventilation

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Pharyngeal pressure measured with a polyurethane air filled catheter inserted into the nasopharynx attached to the Bicore II device for measurement.[Over a duration of one to two hours while receiving nasal high flow oxygen (NHFO2). Measurements made every 12 minutes.]

Secondary Outcome Measures

Name	Time	Method
Work of breathing calculated from oesophageal pressure measured by oesophageal catheter with air filled pressure balloon inserted nasogastrically or orogastrically, and lung volume change measured by respiratory inductance plesmography bands around the thorax and abdomen. Both measurements made with the Bicore II device.[Over a duration of one to two hours while receiving nasal high flow oxygen (NHFO2). Measurements made every 12 minutes.]