Interest of Eye Movement Measurements in the Comprehension of Dry Eyes Symptoms (BOSO)
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 24
- 试验地点
- 1
- 主要终点
- duration between 2 blinks
研究概览
简要总结
Dry eye syndrome is a benign situation however its impact on patient's quality of live and on health system is not trivial. One problem is the lack of correlation between patient's symptoms and physical sign observed on slit lamp examination. Eye blinking is a parameter of increased interest in this pathology particularly its frequency. To date no treatment of dry eye syndrome has a proven impact on eye blinking frequency. However recording of blinks has mostly been performed on short duration (3 to 5 minutes) and the distribution of intervals between 2 blinks is not gaussian but exponential. In this study, it is proposed to use modern eye-movement recorder to measure the blink frequency on longer duration (12 minutes) while reading on a screen computer and during a face-to-face interview before and after treatment of meibomian gland dysfunction responsible of moderate to severe dry eye syndrome.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Moderate to severe dry eye syndrome (Ocular Surface Disease Index> 30) following a meibomian gland dysfunction
- •Not yet properly treated for a meibomian gland dysfunction
排除标准
- •History of other ophthalmological or neurological disease
- •Pregnant or breastfeeding women
- •Patient under 18 years old
- •Patient under legal protection
结局指标
主要结局
duration between 2 blinks
时间窗: 2 months after treatment
Assessment by infrared oculography while the patient is reading on a computer screen and during a face-to-face interview
次要结局
未报告次要终点
