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临床试验/NCT02851654
NCT02851654已完成不适用

Interest of Eye Movement Measurements in the Comprehension of Dry Eyes Symptoms (BOSO)

Fondation Ophtalmologique Adolphe de Rothschild1 个研究点 分布在 1 个国家目标入组 24 人开始时间: 2014年11月5日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
24
试验地点
1
主要终点
duration between 2 blinks

研究概览

简要总结

Dry eye syndrome is a benign situation however its impact on patient's quality of live and on health system is not trivial. One problem is the lack of correlation between patient's symptoms and physical sign observed on slit lamp examination. Eye blinking is a parameter of increased interest in this pathology particularly its frequency. To date no treatment of dry eye syndrome has a proven impact on eye blinking frequency. However recording of blinks has mostly been performed on short duration (3 to 5 minutes) and the distribution of intervals between 2 blinks is not gaussian but exponential. In this study, it is proposed to use modern eye-movement recorder to measure the blink frequency on longer duration (12 minutes) while reading on a screen computer and during a face-to-face interview before and after treatment of meibomian gland dysfunction responsible of moderate to severe dry eye syndrome.

研究设计

研究类型
Observational
观察模型
Case Only
时间视角
Prospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Moderate to severe dry eye syndrome (Ocular Surface Disease Index> 30) following a meibomian gland dysfunction
  • Not yet properly treated for a meibomian gland dysfunction

排除标准

  • History of other ophthalmological or neurological disease
  • Pregnant or breastfeeding women
  • Patient under 18 years old
  • Patient under legal protection

结局指标

主要结局

duration between 2 blinks

时间窗: 2 months after treatment

Assessment by infrared oculography while the patient is reading on a computer screen and during a face-to-face interview

次要结局

未报告次要终点

研究者

申办方类型
Network
责任方
Sponsor

研究点 (1)

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